ID A0A060S9K7_PYCCI Unreviewed; 668 AA.
AC A0A060S9K7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=BN946_scf184845.g52 {ECO:0000313|EMBL:CDO71182.1};
OS Pycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Trametes.
OX NCBI_TaxID=5643 {ECO:0000313|EMBL:CDO71182.1, ECO:0000313|Proteomes:UP000029665};
RN [1] {ECO:0000313|EMBL:CDO71182.1, ECO:0000313|Proteomes:UP000029665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRFM137 {ECO:0000313|EMBL:CDO71182.1,
RC ECO:0000313|Proteomes:UP000029665};
RA Levasseur A., Lomascolo A., Ruiz-Duenas F.J., Uzan E., Piumi F., Kues U.,
RA Ram A.F.J., Murat C., Haon M., Benoit I., Arfi Y., Chevret D., Drula E.,
RA Kwon M.J., Gouret P., Lesage-Meessen L., Lombard V., Mariette J.,
RA Noirot C., Park J., Patyshakuliyeva A., Wieneger R.A.B., Wosten H.A.B.,
RA Martin F., Coutinho P.M., de Vries R., Martinez A.T., Klopp C.,
RA Pontarotti P., Henrissat B., Record E.;
RT "The genome of the white-rot fungus Pycnoporus cinnabarinus: a
RT basidiomycete model with a versatile arsenal for lignocellulosic biomass
RT breakdown.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-
CC O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+);
CC Xref=Rhea:RHEA:67452, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30879, ChEBI:CHEBI:171667, ChEBI:CHEBI:171668;
CC EC=3.1.1.117; Evidence={ECO:0000256|ARBA:ARBA00024511};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:67453;
CC Evidence={ECO:0000256|ARBA:ARBA00024511};
CC -!- SIMILARITY: Belongs to the carbohydrate esterase 15 (CE15) family.
CC {ECO:0000256|ARBA:ARBA00010092}.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO71182.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CCBP010000098; CDO71182.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060S9K7; -.
DR STRING; 5643.A0A060S9K7; -.
DR ESTHER; pycci-a0a060s9k7; Fungal_carboxylesterase_lipase.
DR HOGENOM; CLU_006586_14_2_1; -.
DR OMA; WKEAFEP; -.
DR OrthoDB; 1387367at2759; -.
DR Proteomes; UP000029665; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR43142:SF5; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000029665}.
FT DOMAIN 25..176
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 213..277
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT REGION 184..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 74575 MW; 62250B4FF5C5679B CRC64;
MIAKTFDNVQ EPVVLHEDLK TTFTGIVHPI STPDAPVHQY RGIKYASIPA RFRQSKIFTR
YPPQTDCSRF GPICPQPKFK SVEEELFNLS EDCIPNQAFK QSEFECLNLN ITCPADATPV
SQYPVMIWIH GGGNRGSGSN WVTDAGPLVQ KSMQISRPVV IVSINYRLGL FGFAASPALR
DDNKAAGDEG VGNYGKRPPT PHAPTSLNSV HVLGLRDQRR AMEWVHRYIH AFGGNPNNIT
LFGESTGAGD ILCHLHSAAN EVAPLFQRAI IQSAIVDLEV PNLHQVGWQM SKLISALRVQ
SVDELRAVDA EKLVLLGQGI RAVDDGVFFR KSWTGSLASL DKTASRHHVE KCLGDSLVVE
LNSHFHRTKV PQRLHEHPRS RSYTRHASHQ PVIIGDCGAE SLLWSLPASL WTAAGVVKRI
QAICQSLNKA SMLLRLYDIS SCTPADELPE RLLDLINDTR FAWPTELIAA SLRAERGGHG
VWRYVFDQEG PSRGLPHHTV DLMYLFDNVP LPALPTASAY DIITPREDGR FYTPDDSDDE
DCPAAKSSVR LPPAVNARDS DSEDETPGYD YDTDWAMPVV DDWTYARVRN TIQERWLAFA
YGEEPWREDK VFVFGPEGEV GERSMCIFEA RRRKQTWKEA FEPLGMDVVQ KLGVELCNGP
PVDARSCY
//
