ID A0A060SH92_PYCCI Unreviewed; 1060 AA.
AC A0A060SH92;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=BN946_scf185014.g46 {ECO:0000313|EMBL:CDO73576.1};
OS Pycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Trametes.
OX NCBI_TaxID=5643 {ECO:0000313|EMBL:CDO73576.1, ECO:0000313|Proteomes:UP000029665};
RN [1] {ECO:0000313|EMBL:CDO73576.1, ECO:0000313|Proteomes:UP000029665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRFM137 {ECO:0000313|EMBL:CDO73576.1,
RC ECO:0000313|Proteomes:UP000029665};
RA Levasseur A., Lomascolo A., Ruiz-Duenas F.J., Uzan E., Piumi F., Kues U.,
RA Ram A.F.J., Murat C., Haon M., Benoit I., Arfi Y., Chevret D., Drula E.,
RA Kwon M.J., Gouret P., Lesage-Meessen L., Lombard V., Mariette J.,
RA Noirot C., Park J., Patyshakuliyeva A., Wieneger R.A.B., Wosten H.A.B.,
RA Martin F., Coutinho P.M., de Vries R., Martinez A.T., Klopp C.,
RA Pontarotti P., Henrissat B., Record E.;
RT "The genome of the white-rot fungus Pycnoporus cinnabarinus: a
RT basidiomycete model with a versatile arsenal for lignocellulosic biomass
RT breakdown.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO73576.1}.
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DR EMBL; CCBP010000122; CDO73576.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060SH92; -.
DR STRING; 5643.A0A060SH92; -.
DR HOGENOM; CLU_000335_0_4_1; -.
DR OMA; LEMIACA; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000029665; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000029665}.
FT DOMAIN 79..266
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 695..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 895..913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1060 AA; 118453 MW; 70F70470FC4CDF93 CRC64;
MKLRGSTVRF LVISATVPNI MDVADWVGNR ANNGPALVKE FGEEYRPCKL SRFVYSVPRR
RDANDFIFAK ALDFKLYGVL QQHCNNKPVL VFCPTRKGVM SAAELIHKEY EEAIAKKQTL
PWSKPPHIEH SFSNKQLDKL AACGIGVHHA GIVREDRTAT EQLYLKKALK VLFATSTLAV
GVNLPAHTVI IKGVKLFQNG ASQEYSDLDV MQMIGRAGRP QFDKEGVAII MCEQDLEVKY
KALAQGQTIL ESSLHLHLPE HLNSEIALGT IKDMVSAKEW LHNSFLFRRI QKNPLHYDIR
KEGNKSWEQR MDDLVADSVK TLKDTDLVTH EGEDDRLSST EYGDIMSKFY IRQATMVTIL
KLPDTASVRE ILEAISCADE FSDIKFRAGE KQVYNKLRIH QDIRYTLKKI EKPSDKVFIL
IQAILGAINL ADPEYRTGES QPYTESLPIL RHISRIARDQ LPQYTIAISE EEVSVREDGV
EVELLIECGL AQNTKVQKSK KPKKQRRWDM TMMLTLTSDN TFIDFRRIST VALRESRTFS
VTAKLTKPSQ AVIVYATSAW TQQASLSWIP VRRTHWCIIL VPPHLIDADE LEKARDLEGL
EDIADFWDMS PDEDATPGGA TRLSKDAALD QDGTPQFTSN RGVMSAPKQL QNGNYECNHT
CKEKARCRHL CCREGLAKPP PMTKKRIEML IAAADKSPRK QDGEGQDHTV AQPGIDAQDA
RSKPKPRMKE PHKPVAVDAN RSLKKLEALH ERMGVEKSLQ LAEGIRIKLN TEYPSYSQQP
FRKSKPEFDV EYSTLQNGSS VANSGVSVVL SDSDDDLPEP GGVFSSVPKI TTGLKSSPDS
TDYADPDFDA LIAGLPVCEA GHTSNAVGRR ATPTNTRFSM SNDDRLSSTT DWLPDTPSRK
RKTEHDGSRP YKRQKNDVAA SPSQDAVSLD RGSTLGEPLF EQALSDDMHS LFETRGSRSS
ASSVAPALVD DGDSFVLDTS LFDIMPSTPT WTERNRDEHS KADSQVALGH HASTETRFVK
THLNISRSPK PTDPEPEEVD DPLAELEAWL QSGAVEIGEE
//
