ID A0A060SL38_PYCCI Unreviewed; 1035 AA.
AC A0A060SL38;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=MutS protein homolog 3 {ECO:0000256|ARBA:ARBA00029792};
GN ORFNames=BN946_scf185004.g26 {ECO:0000313|EMBL:CDO74876.1};
OS Pycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Trametes.
OX NCBI_TaxID=5643 {ECO:0000313|EMBL:CDO74876.1, ECO:0000313|Proteomes:UP000029665};
RN [1] {ECO:0000313|EMBL:CDO74876.1, ECO:0000313|Proteomes:UP000029665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRFM137 {ECO:0000313|EMBL:CDO74876.1,
RC ECO:0000313|Proteomes:UP000029665};
RA Levasseur A., Lomascolo A., Ruiz-Duenas F.J., Uzan E., Piumi F., Kues U.,
RA Ram A.F.J., Murat C., Haon M., Benoit I., Arfi Y., Chevret D., Drula E.,
RA Kwon M.J., Gouret P., Lesage-Meessen L., Lombard V., Mariette J.,
RA Noirot C., Park J., Patyshakuliyeva A., Wieneger R.A.B., Wosten H.A.B.,
RA Martin F., Coutinho P.M., de Vries R., Martinez A.T., Klopp C.,
RA Pontarotti P., Henrissat B., Record E.;
RT "The genome of the white-rot fungus Pycnoporus cinnabarinus: a
RT basidiomycete model with a versatile arsenal for lignocellulosic biomass
RT breakdown.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|RuleBase:RU003756}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family. MSH3
CC subfamily. {ECO:0000256|ARBA:ARBA00007094}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO74876.1}.
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DR EMBL; CCBP010000220; CDO74876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060SL38; -.
DR STRING; 5643.A0A060SL38; -.
DR HOGENOM; CLU_002472_0_2_1; -.
DR OMA; HIAPCEL; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000029665; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF122; DNA MISMATCH REPAIR PROTEIN MSH3; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 3.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029665}.
FT DOMAIN 908..924
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1035 AA; 115558 MW; 4B75DFDD27016DDF CRC64;
MSRTPKKSGT QPTISSFFSQ SSIGASPAGS TLKSQSASKN KRGSSPIDLT LDSGDDAAAP
PLKRQRTTTS TFFSPRKPSN SSPQPASPGK RAAGHAERWR FELHTPSVAA ATQRDETQRL
LHERAKRILL GNDNVFSTER LSADATPSSD VEDNPEVQDA AHEDDIEENE KKFSELMDMF
GSSAGKRKGK GVTRKAVPSA AGPSRSRSQK VEEVGPSGQT YTPFELQRNL HTAMIPLHRR
DVHLKKLLSQ GYKVGIVEQT ETAALKKASD TRNELFEREV TQMYTAATFV DDLNSLDELD
PNAAPPLMCL LEEPRGGMGA DERVNIAMVV IAPSTGDVVW DEFDDNHMRT ELETRMVHTK
PYELLLPAKK LSVPTEKMIH QFAEHSHTEH RMRVERFSKQ MSYTEAFALL SKFYKGKERL
SDDSRGADTG GLADALADFS KLVVIALAHA VKYLSTFNIA DALRETRFFA KFTERTHMLL
NANTLTNLEI YRNETDYSTK GSLIWILDRT STKFGARLLK SWVGRPLIDP HALRERTEGV
EEILGNRSPK LTLLRELLRR LPDLARGLCR IQYGKCTPQE LTVLLKAFRR VSSAFAPPHP
AQSQQTTPSA GLKSQLLIGI VELLPKLRDP IKEICDAIDF SAAEQGKEDA MWTDIDRYPE
LDSLTASIQV VESELVDELK AIRKLVKKPA LQYTTWNGEE YVVEIRKDER REVPANWTLL
SSTKYVRRYH TPQARVKLQE RAQYKEALAA EARKAFLSFL AEITEKHYAL LRDAVNKLAV
ADCLFSLAQV AAQEGYCRPD FAEGAKACEA QEDVLEIIDG RHPMIEALRT DPFVPNSLKI
GGKETRHKVD RLMAQVGSYV PAKSMRMSLL DSVLTRMGAF DELARGRSTF MVEMQETSDI
LRMATPRSLV VLDELGRGTS TFDGMAIAGA VLQHLVDSVK CKTLFITHYP QVATDLERMF
PSEVGNMHMG FTEETRIDGS REVTFLYRLE PGLVAESFGV ECARLAGLPG SVLQIATSKA
ANMRRLIEER VRRTK
//
