ID A0A060VSZ3_ONCMY Unreviewed; 4697 AA.
AC A0A060VSZ3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Hydin adenylate kinase-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSONMT00076258001 {ECO:0000313|EMBL:CDQ57972.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ57972.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ57972.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ57972.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FR904294; CDQ57972.1; -; Genomic_DNA.
DR STRING; 8022.A0A060VSZ3; -.
DR PaxDb; 8022-A0A060VSZ3; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 21.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031549; ASH.
DR InterPro; IPR033305; Hydin-like.
DR InterPro; IPR033768; Hydin_ADK.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23053; DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1; 1.
DR PANTHER; PTHR23053:SF0; HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG; 1.
DR Pfam; PF15780; ASH; 1.
DR Pfam; PF17213; Hydin_ADK; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 203..300
FT /note="Abnormal spindle-like microcephaly-associated
FT protein ASH"
FT /evidence="ECO:0000259|Pfam:PF15780"
FT DOMAIN 1658..1851
FT /note="Hydin adenylate kinase-like"
FT /evidence="ECO:0000259|Pfam:PF17213"
FT REGION 641..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1947..2076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2257..2350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2125..2152
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 956..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1947..1994
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1995..2009
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2011..2057
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2263..2279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2287..2315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2319..2350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4697 AA; 524005 MW; 9BE8C7F0A3499CFE CRC64;
MANQRSVSIV NRSDTLVHYQ WKSLATKEEE EQQKLRFCSE LQREEEDDMD QFLTECDADP
TLRDRLSLLS RTFQDRRRQL KEERLSFSDN YITVEPLEGD IWPNTTSEVN IIFKPQEAKI
YQQTVYCDIT GRESRLPLRI KGEGLGPKLQ FNFDLLDMGT IFIGSNHSYE VLLSNNGLIE
ATFKLVPPSS GFGQCFSFSP TEGMVPAGAC QAMEVCFSSS TLGVFSEEFV FTVGGNPQPI
SLTFRGCVIG PTFHFSVSEL NFGDVSFGFP HTLTCSLNNT SLVPINFGLR VPGDGSGPSS
ITSVSQVSDL SRTEWSSSTV PDRPIEFTLT PNSGTVRPQG LVDIQVTLCS NSVQRYSLAL
VVDVQGVGED VLALPINARC VIPNVLLDTP VLQFQRCFLS YPYEQSVKLT NDSDLPACYG
LLFQEYEEYP SLLYSSAHPR GVIQPHSAVD IPLALRAKTV GRLQQTAQIA IFGKKEPPLN
LQLSCIGEGP VVHVMTTEVA FGSIPVLTDV SRTLQLSNQS PIPARFVAQM VRSRSLWRVE
PSEGEVPPQG KLELRLVAHL DDTLHFQDKL HLSIQNSETH TIPFSATGKG TTIVTNRPFA
PSLDLGAHFS SGPCQYHFRV TNRGRRSHQL YWTTDGYPQF RRRVPPPANT TREGKGRSSL
VPPPVDGPVF SLHPMRMELA PGHTADMVLE GSSDSPKVVR ERLVCHAILG HQSGKERIMT
VDVTCRFVSP ILDISSQQLS FYVEKAPGVS LLPLYQKLLL RNVSSLALSL QLTLAEPFGL
SDHDGDHTCV TSKTLVLAVG VQTEQWVRFD PLYRQDSMTR VAEEVLEVRY SDHPQQDTVG
LRGEVHFPNL HFSSAALDFG CVLNHTEVQR QLTMTNCSPL SVSYHWAFLV DQQQYNIRFP
EQTNVSEGRV TTHEEERDTR WDLSKTRNID IRVDSNRSDP AVHQAPALAP CSYNPSRREI
NRTSPAQWPD STDQNTGTAS RTTKDHPSVG VEEVFDILPI YGVLQPGESQ LVSFSFYGHA
DISGQVLALC EVEEGPTYEI TLKGEASLVT YSLNRTEIDF GLQLFDHVAE AEITLRNTGK
VGFQFSALLG EKDVCEDPRP GHPLVIPRMG YIEANAEQKL SVYYLPGVPE VFHKTFQLQV
AFFEPESLTL RGEGIFPRVC LDLPRELNDE RYTAVVKEAK EALEEDRRDV AISRPATGNG
NLSDKDYIPT YDALLQMEVE RLLVKQNAMA VENRQVNNRD TPASTSKWRK KLSRFLLPEY
TLDFGYVIHG SVPNHIVKVT NTGPMSVSFR ADRRPLTGTG FVVELDRVKN LPYCETETFE
VKFDPRGANL NLGEINTVMP IQVVGGPAVQ VHLCAVVTMP SLTVSTDTLQ FDSIQCGLCQ
VTTVQLFNPE PVPCEWSIAE EQRPRKKIDK HVPLHLRRKA RLEQCPPPVV FEMLPSTGVL
YPGDRVNVQV KFSPAEGRAY SQRLVVSVAQ STQRMLLLAQ GQGEEPQLEF SSSVLELGPT
LPFSAGEEAE VIVRNPCPFP IEFYSLEFDK KYLEEDKILR MMKGYDVQNV LLLPPRAPGE
SLPPEIIDYY NEHNWDKGEQ EEELATPPLP ERLVEEEKEA APSKDGTPCG DLIKDTVESR
TASVGDLEVN PVSRAIARHM GIDLSPEGQA ARNRRGIAII VHGAPLSGKT GTAVTLAKYY
GAACLNIDAV VLEALSSGMT SAGLRARELC AKAAMEHAQK RVEEAGQAVV EVMGPAGQGA
GTLSVEAVAK HTAEGSQVID PKAPASSIST RNKNSVVGGK RIDGSQPTAP SMCLLSVQGG
GPIHRQLSIS VSQVGELGLM SCLLPDQLLV DILSERLQLS DCHRGVVMDG LETLYSLSPS
STLQIILKAF NNRSFIYMVN LSNNYYAFKA KERAQREAEE VLQREHAEKE KLRLQEMDEE
EYDALPEEEK ESIDLRHLVA LRERKRREQE RAEREQEERR QQEELERVRE EEEMKKKNKK
GKKEPAKDDS SGKKSQLGGK QSASALRSET KLDQPVKDGR KMSSCADGKE YKDSPTEGTR
EPEEGPKKKK PKEGKAGGQD ESPLPSEDPE RELSSEGDRL LLSRFRLYEQ SQPQLLHILQ
FWDRAQGQLL QPLFSEDNIQ EPEEVTKKER EKEKVEKEKE RLEKEKLKAD ATDVKLVSPA
PSQALLAVEG SEGGDREAAP ETVPHILLSV TGRDYLSGIE ILKSNKLPPL EEVLDGLGLG
PKGPPIPPST IFSVIPYPKK RPVPSAQQIT SCFTFMVPSV PEDPTGEKKD TDMEAEAQGS
VKEEVVTPTK GRGKKADTGR ESQKDKRRTP AKKGARSNDS RSPPLNAVTP LSDTEHCQQE
SQQERNQRLT TFRWNVPPNG EVTLKIWFHS QLPGKFDQTL NFELLGTKRR YQMYCRGICA
YPSISKDVKM VFAHSKRVLQ SDEVLQKTYI IRSGLYEFGP LLCGKTRDRY KERKYPENME
RLVIHNNSPL DAEIHFCFQH DTKATTYLLD PPNMTLKPNE RQELTVWAYP TSPGQIEDSV
VCCIKENPEP AIFRFSCRGV RPELEIERKQ LHFDKILLHR KDTRNLCLRN NTLLPAAWRL
SGLEVLGDEF SVSQDQGIIL PHSEFCLQMH FRAMKPINLK RAIRLEVSDV ENILGIVHTE
NIQILAEAYD VALDITFPKG ADGGLDFGTI KVSEEVKLSV NMKNKGKYEI AFKFILEATD
PAVPDLNQIF TITPQKGSLN PNDRPTCVQF VFRHNKEVSI REQPILRCQV IEPNIAEGGE
TIAIIPIKVS VRSLFSKYNI MPSSDINFGP LVYGCRKTQT FTIENKGDFE IRFNISRMCK
DLPQPAQRRG IVGKRTSREN HSAKPLTGNK VRRTESIQKD MGMSTLARFT MGVFSLVPGF
GTLAPGAHQV VTVDCVAEQA GRWQECLALD ITDRDPSDNP GGIPYRLVAE VCMSGIAYKD
IASIFEEHRI CKTSTMLYCE QFRDSMGIYI QDENKFVFNN VLVGRPAKAR FRLTNNGKVP
CELSLAVKPI SVRSTEVFEL TPGRLSIPSH SHAFAIITFA PQTMQTYHAV FEATLEGATS
LQPMAKSKVL VFDLMGDGNL PSVTILRPVL RTSRGHPLLQ FKRLLVGRAQ TLPLVLKNEV
NVPAQVRTSS VYITFLEQQM AHTASLVLLG GQQAEFEVEF SPVVAQSFEA NMRLLVVDNQ
YEETVVRLLG EGYHDVISLD NINSKAQQKE YSPDGKGDLL FFGDCDVSRP YQETFTMTNL
SSNNVLRFEW PADGPQVSFS PQVGHLHAGC AKEVTVTFCS EQPVVLIAQP VKCKLCRVVF
QQPVDQVPDW DDRLRTVKWV DSGKQVGSQQ PTKKKVIETD PEPVHSVVEK SFRETELRIS
AVCDYAKFTC NAETIRFKDT LLYQTRMFQL QMVNNGSVKL EYSWQVLMDR YGKGVNFDHG
DVSPRSCQSS RLGVRPASSL ESVSCLMLGD PDLPPFSVEP SVGIISPGAT QTFRIKFSPF
EVAECEARLV CSIPNLKDEQ SPTMVVCGRS LLPYCHFHLE DSDYISGNRR NPELRGPHGA
LPRAPLDPNT RVIEFRSVGI GSSILRWFSI VNPTNKPYSF IWRCEDAGAS PFQCLTPNNS
IQPGKKVEVS FEFQAQEPDT VESFWTFLIP DQNLSVPFLL VGTASEPVVY MDHAHLNLGN
LLVGHKAHQT VYLLNGENQP FQFFIKETSR YSEAFLDSLQ LEPMEGVVPP KDRFPVFVSF
TPTQDGVVTF NLLVQVKGKV QPLNMNIKAE GYSMNACVQC ESTEGGVTEL SPGNSYHQVD
FKQVELSDTT LCTFLVSNLG KFSLDVQYEL WGSAEMQRHL KVETDKGRVE VGRQSRCTVT
FFPLQKCVLK DVGLNIKIKN GPVFSCSILG SAVAPGLDFS FSKHNFGMSF IYCAGMVPAT
HTLIISNKGE RGISLDCQFS NTPFLEVGFQ PEVLPPGGSM EVPITFYPRE AMRYHERVVF
EINDCAKQMV EILGQGIEMK VDFEDPRHKL VNLGAPQIGQ KIRRVIPLVN NSHSSLTFSL
LLSSTVHTLL DSRVLSVNPP GEVTLKPFGG RCLVEVLFSP RQRMAPFTSE LQFECLGTVR
PLLVLKGCCQ GVEVKLDQDY LPFGAVAQRC KVTRRIIMQN TGDIGARFQW EMKRFGRDFS
ITPVEGYICP GMEVPFEVTF SPVELSHELR YDDLPCSIEG AKPIKLTLAG SCILPPVTKE
VLHFVCQVRC QHIQSLTLSN RTNQRWTLKP VMEGEHWSGP PSFIIEPYQQ NKAYEITYKP
MVTTADGKKH LGSVFFSFPD GTGMLYTLHG TAEAPKAVAT ITHEMPSKTQ YTEMVPVQNW
LSKPQRFRAV VEIMKPERPD STVSLKGLDY LDVPALAKRD YKVSFFTYKE GQYNAKVTFR
NESTGEYLFY YLNFKATAPG VISTIEMVTP VRQTASASVR VENPLPISLF FSAECRSPDV
SVPPQLSTPA LSKATLSFEY QPLRAGESTA RLILHNGELG YFHYELLLKA LPASHEKPLY
FRAPLGSGHS VSAKFTNYSR VKAEYACKTD SPDFIVEKNI NAAAGYQAGT DISLEVYFEP
CQLGEIRGML TLSSGFGGEY MFPLFGCCTP PKAQGPFTIR AGSSVSIPFK NVFVQTTAFS
FQVDSPSFTV KGVETIRSKK THNILVMFEG PPPGSRGPCS GKLTISSPRS EGHGQSISWV
FYLKGYCPEL AQRDKTS
//
