ID A0A060VUZ5_ONCMY Unreviewed; 1021 AA.
AC A0A060VUZ5; A0A8C7NZ66;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 {ECO:0000313|Ensembl:ENSOMYP00000014475.2};
GN ORFNames=GSONMT00078482001 {ECO:0000313|EMBL:CDQ58778.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ58778.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ58778.1, ECO:0000313|Proteomes:UP000193380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ58778.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSOMYP00000014475.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
CC {ECO:0000256|ARBA:ARBA00009687}.
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DR EMBL; FR904311; CDQ58778.1; -; Genomic_DNA.
DR STRING; 8022.A0A060VUZ5; -.
DR PaxDb; 8022-A0A060VUZ5; -.
DR Ensembl; ENSOMYT00000016019.2; ENSOMYP00000014475.2; ENSOMYG00000006770.2.
DR GeneTree; ENSGT00940000157297; -.
DR OrthoDB; 5482994at2759; -.
DR Proteomes; UP000193380; Chromosome 10.
DR Proteomes; UP000694395; Chromosome 10.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0031491; F:nucleosome binding; IEA:InterPro.
DR CDD; cd00167; SANT; 2.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.20.5.1190; iswi atpase; 1.
DR Gene3D; 1.10.1040.30; ISWI, HAND domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR015194; ISWI_HAND-dom.
DR InterPro; IPR036306; ISWI_HAND-dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR015195; SLIDE.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR PANTHER; PTHR45623:SF49; SWI_SNF RELATED, MATRIX ASSOCIATED, ACTIN DEPENDENT REGULATOR OF CHROMATIN, SUBFAMILY A, MEMBER 1; 1.
DR Pfam; PF09110; HAND; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09111; SLIDE; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF101224; HAND domain of the nucleosome remodeling ATPase ISWI; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51293; SANT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 157..322
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 452..603
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 807..859
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 982..1021
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..802
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1021
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1021 AA; 119020 MW; ADE18CF42A123F59 CRC64;
MSDEEIPSTS REPLPEDEEA KDPPFQLKPP PKALPKAEGE VDPEYEEKRK TDRANRFEFL
LKQTELFAHF IQPASQKSPT SPLKVKPGRP RVKQDEKQNL LSVGDNRHRR TEQEEDEELL
SESRKAANVL VRFEESPSYV KNGELRDYQI RGLNWMISLY ENGINGILAD EMGLGKTLQT
IALLGYLKHY RNIPGPHMVL VPKSTLHNWM NEFKRWVPTL KAVCLIGDKD ARAAFIRDVM
MPGEWDVCVT SYEMVIREKS VFKKFNWRYL VIDEAHRIKN EKSKLSEIVR EFKTTNRLLL
TGTPLQNNLH ELWSLLNFLL PDVFNSANDF DSWFDTNNCL GDQKLVERLH AVLRPFLLRR
IKAEVEKNLP PKKEVKIYLG LSKMQREWYT RILMKDIDIL NSSGKTDKMR LLNILMQLRK
CCNHPYLFDG AEPGPPYTTD THLVTNSGKM VALDKLLPKV QEQGSRVLIF SQMTRVLDIL
EDYCMWRGYE YCRLDGNTPH EARQEAIEAY NADNSSKFIF MLSTRAGGLG INLATADVVI
LYDSDWNPQV DLQAMDRAHR IGQKKPVRVF RLITDNTVEE RIVERAEMKL RLDSIVIQQG
RLMEQSNKLG KDEMLQMIRH GATHVFASKD NELTDEDINT ILERGAKKTA EMNERMESLG
ESSLRNFTVD TGGAETSLYN FEGEDYREKQ KLSMMEWIEP PKRERKANYA VDAYFREALR
VSEPRAPKAP RPPKQPNIQD FQFFPPRLFE LLEMEILFYR NTIGYKVPRS PDISNSAQVQ
KEEQRKIDEA GPLSPEETEE KEKLLTQGFT SWNKRDFNQF IKANEKYGRD DIDNIAREVE
GKNPEEVIEY SAIFWERCNE LQDIEKIMAQ MERGEARIQR RISIKKALDA KVARYKAPFH
QLRIQYGTNK GKNYTEEEDR FLICMLHKMG FDKENVYEEL RQCVRNAPQF RFDWFIKSRT
AMELQRRCNT LISLIEKENM EIEEKERAEK KKKTPKSQTA HKRKADASSE GTGRKEKKAR
A
//
