ID A0A060W6B7_ONCMY Unreviewed; 388 AA.
AC A0A060W6B7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
GN ORFNames=GSONMT00067449001 {ECO:0000313|EMBL:CDQ62586.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ62586.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ62586.1, ECO:0000313|Proteomes:UP000193380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
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DR EMBL; FR904412; CDQ62586.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060W6B7; -.
DR STRING; 8022.A0A060W6B7; -.
DR PaxDb; 8022-A0A060W6B7; -.
DR Proteomes; UP000193380; Chromosome 5.
DR CDD; cd09942; SH2_nSH2_p85_like; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR032498; PI3K_P85_iSH2.
DR InterPro; IPR035022; PI3kinase_P85_nSH2.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF1; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA; 1.
DR Pfam; PF16454; PI3K_P85_iSH2; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00678; PI3KINASEP85.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 185..280
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
SQ SEQUENCE 388 AA; 44007 MW; 9ACE368D5815ECB5 CRC64;
MPSLKHTIRT VKRIVYILES LRNAKQNMLI WHWIENNVAY LPLSTAKALR LSLNLLAGSC
IQELSVGETG RRLLKALEPP AVPLPSLHYL LRHLDRVGQG LAHNGQSSAH NGLDPHTLAF
LFSPLLLTTG SEEGHQVQVL ERLLVARAWE LDQMSSALPS KPSKTKAMAS SVVNGDGSKM
ADAEWYWGDI SRDEVNDKMR DTPDGTFLVR DASSKVQGEY TLTLRKGGNN QLIKIFHQGG
KYGFSEPLTF ASVVELILYY HHESLAQYNP KLDSRLLYPI SKYQQDQVVK GDSVEAVGEQ
LKVYHEHCQE TSREYDVLYE EYTRTSQELQ MNRTAIEAFN ETIKVSEEQC ETQEGYSKEN
IDQFLREGNS KDTERYPQYI ACSKIFLL
//
