ID A0A060W8Q3_ONCMY Unreviewed; 1032 AA.
AC A0A060W8Q3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Unconventional myosin-Ih {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSONMT00082729001 {ECO:0000313|EMBL:CDQ60935.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ60935.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ60935.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ60935.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; FR904364; CDQ60935.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060W8Q3; -.
DR STRING; 8022.A0A060W8Q3; -.
DR PaxDb; 8022-A0A060W8Q3; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF353; UNCONVENTIONAL MYOSIN-IH; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 12..694
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 849..1023
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 571..593
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 105..112
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1032 AA; 119075 MW; B9CD5D4B5151409D CRC64;
MEGSLTARDR VGIQDFVLLD AYTSESAVLD NLRKRFNENL IYTYIGTLLV SVNPYKELGI
YTKKQMDIYM GVNFFELPPH IYALADNVYR TMLTETNNHF ILISGESGAG KTEASKKILQ
FYAVSCPSTK LLDNVRDRLL LSNPVLEAFG NAKTLKNDNS SRFGKYMDIQ FDHMGGAVGG
HILSYLLEKS RVVHQNHGER SFHIFYQLVE GGEEDLLRWL GLERNCQRYS YLVQVGEGEC
AKVSSVNDKS DWKTVRKALS VIEFSESNIE SLFAIIASVL HLGNVTFVAD SQGYATLNNS
PEIHWLSKLL GIPAQVIQVG LTHRKIEARS EEVLSPFTVD QAVYAKDALA KAIYGRTFTW
LVNELNESLA NKDSSRKTVI GLLDIYGFEV FSVNSFEQFC INYCNEKLQQ LFIQLTLKSE
QEEYEMEGIE WESVPYFNNK IICDLVEAKF KGIISVLDEE CLRPGEATDM TFLEKLEEKM
GGHAHFVTHK LADQKTRKTL ERGDFRLLHY AGEVTYSVVG FLDKNNDLLY RNIKEVMRQS
KNAIVKHCFP STEPDSKKRP ETVATQFKSS LVGLTEILMS KEPWYVRCMK PNEGKQPGLF
DDVLVRHQVK YLGLMEHLRV RRAGFAYRRR YEIFLQRYKP LCPDTWPNWK GTAAEGVECL
VKHLGYKPDE YKMGRTKIFI RHPRTLFATE DAFEVCKHEL ATRIQAKYKG YRVKGDYMRQ
RQAATKIETC WRGMKARRER EKRAWAVKVI KRFIKGFMTR NQPACVDNTE YLAFVRQNYL
TRLKENLPKT VVDKNTWLTP PPIMQEASQM LRKLYTRHMV RRYVQGIMTE RKAQLQIKGL
TSSIFKGTKE NYPHSVGIPF VDTRISEEDI HIKVYQMIRQ ERIKYSVPVV KYDRNGFRPR
FRQLIYTGSA AYLVEEAKIK QRVEFNNLKG VSVSTLSDNF LILHVQCEDI KQKGDLVLQC
DYLFEALTKL CLVANKHNFI KVVQGSVKFD IQPGREGFVD FKSGQETMIY RAKNGHLMVE
STRTKSRAMI QN
//
