ID   A0A060WDP2_ONCMY        Unreviewed;       987 AA.
AC   A0A060WDP2;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=PKD domain-containing protein {ECO:0000259|PROSITE:PS50093};
GN   ORFNames=GSONMT00072629001 {ECO:0000313|EMBL:CDQ65131.1};
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ65131.1, ECO:0000313|Proteomes:UP000193380};
RN   [1] {ECO:0000313|EMBL:CDQ65131.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24755649; DOI=10.1038/ncomms4657;
RA   Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA   Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA   Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA   Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA   Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA   Guiguen Y.;
RT   "The rainbow trout genome provides novel insights into evolution after
RT   whole-genome duplication in vertebrates.";
RL   Nat. Commun. 5:3657-3657(2014).
RN   [2] {ECO:0000313|EMBL:CDQ65131.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Genoscope - CEA;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FR904496; CDQ65131.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A060WDP2; -.
DR   STRING; 8022.A0A060WDP2; -.
DR   PaxDb; 8022-A0A060WDP2; -.
DR   Proteomes; UP000193380; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 3.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR029865; KIAA0319-like.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR002859; PKD/REJ-like.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   PANTHER; PTHR46182:SF3; DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN; 1.
DR   PANTHER; PTHR46182; FI19480P1; 1.
DR   Pfam; PF02010; REJ; 1.
DR   SMART; SM00089; PKD; 4.
DR   SUPFAM; SSF49299; PKD domain; 3.
DR   PROSITE; PS50093; PKD; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        864..889
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          445..505
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   REGION          107..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          900..987
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..181
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        903..920
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        940..965
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   987 AA;  107505 MW;  3893F266B668F3F5 CRC64;
     MALITSSLYT HCVSAEICRV TGGVLGIHWS SVVDLGWRPL AVGRGSASCW DSCCLEPACS
     AVWSLGGHCV LLNCSNRGVC EVTSLPQPHI ESLGLLQLFS KGTTTARRRR LRRAQTGKGS
     EAVSQKHGSD HKRSSTNHSQ LTDGSGEAPS PSQQNSKSED TIGPASSNSS SVLPANAPTI
     TTSPTQAVRE LVVSAGESVE VTLPRNEVEL NAFVVPAPQP GTDYAFDWLL RTHPKDYSGE
     MEGKHSETLK LSKLTVGLYE FEVTVDGDGA HGEGYVNVTV KPEPRVNKLP VAVVSPKFQE
     ISLPTSSTVI DGSQSTDDDK VVAWHWEEVK GPLREEKVSA DTQILTLTGL VPGNYTFRHC
     YLVFSMGNAS SCIFSTYCFI FLEVLLSIFL TVTDSDGAQS STQATLSVNK AMDYRPVANA
     GPNQVITLPR NAVTLHGNQS TDDHEPLAYE WSLSPESKGK VVEMQGVRTP ALQLSAMQEG
     DYTFQLTVTD TAGQQDTAQV TVIVQPENNK PPVADAGPEK ELTLPVDRTT LDGSKSTDDQ
     NISTYHWKQN KGPDGVKIEN ANGAVATVTG LQVGEYEFSL TVTDERKLAS TDTVTVIVRE
     ELDQPPVAHV QSRPAISLPL RTAALDGSHS TDDKGGVGYL WTRDDSSPAA GDVLNNSDHQ
     AVLFLTNLVE GKYSFTLTVT DSKGQSSSDR GTVEVKPDVW QRDLVELVLE VSVSQVSHRQ
     RDMLLRQVGV LLGVLDSDII VREVSAFNEH RSAPFLYVSG LFISTHSTLL AHTRLVFLVS
     GGPGRPPLSG HSVALGLRNK LRKQKNDFLI FKARRVDTVI CQLNCSSHGD CDSFTRTCVC
     HPFWMENFIK GQLWDQESNC EWSVLYVTIA SFMIVVAIAT FVWGMVCCCR GRKGKMRHKS
     KSRYKMLNGE EQDGLELHPP RAGRMKPAPA PSSSALMRSD SDLDSDDGQG GVPWTDRERG
     HLLRPHNGTL ENGQGPTRNK KQREELL
//