ID A0A060WDS4_ONCMY Unreviewed; 348 AA.
AC A0A060WDS4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 08-NOV-2023, entry version 35.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
GN ORFNames=GSONMT00072663001 {ECO:0000313|EMBL:CDQ65156.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ65156.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ65156.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ65156.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; FR904496; CDQ65156.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060WDS4; -.
DR STRING; 8022.A0A060WDS4; -.
DR PaxDb; 8022-A0A060WDS4; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF119; BONE MORPHOGENETIC PROTEIN 8A-RELATED; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 211..348
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 348 AA; 39096 MW; 0ADD522AD1A060AD CRC64;
MLDLYHAVSA KGDEGNGMGN WVGDGLTGHV SHAALPTLNT YTAPLGTVVS EADTVMSFVN
LVEQERDLLQ PRPYWKEFRF DLTPLPQGET VTAAEFRIYK TLTMGQRANR SLHISVYEIQ
RENKHREPEL VLLDMQSVPA GQEGWLAFDV TSASNRWLLH PRSNLGIRLY VETEEDRSLS
AGWVGLVGRR GPRSKQPFMV TFFRASQAPC RPPRAVKPNP HKKKPKYDLP LPSIHDHSHV
NSGRQACKRH ELYVSFSDLG WKDWVLAPTG YSAFYCDGEC LYPLGSCMNA TNHAMIQLVV
HLLKPDEVPK ACCAPTKLSP ISVLFYDDNN NVILKKHRNM VVKTCGCL
//
