ID A0A060WFW2_ONCMY Unreviewed; 836 AA.
AC A0A060WFW2;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 08-NOV-2023, entry version 29.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDQ65896.1};
GN ORFNames=GSONMT00074259001 {ECO:0000313|EMBL:CDQ65896.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ65896.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ65896.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ65896.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR904521; CDQ65896.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060WFW2; -.
DR STRING; 8022.A0A060WFW2; -.
DR PaxDb; 8022-A0A060WFW2; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR042849; ARHGEF33.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR46944; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33; 1.
DR PANTHER; PTHR46944:SF1; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..836
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035207061"
FT REGION 227..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 81..108
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 227..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 93800 MW; 259AC48100C8B6ED CRC64;
MKDCQKPSSS IPLFLLSLSL SLCWTSPAII PQGPFLCGGS SDSWFRATDR RPVFRRRTEN
TTQPCLLTRQ VGTGTMENGK SDEQDQEMEE ANLEIAQLQA LVVELRTGLQ GVLQDVSVLQ
QRGRGLEERA QGQQSEVDDR IMGIRNSLNT FKEDLSGALS QIKEVTSRQK ELQKGLELLQ
SETGREILSV QQRKSSKGDC IGEGHGCLSN QTELNVIQHY FASLPSCSPQ MSTASTQTSN
SEQDAASGQP QRAQSKSPVW RERKESRDDT DAQSVPENGK RQVAALELLE SERVYVSYLS
LLLKANITFN SSEALHTKDK RPFPSSLRFL IQQHLELLHT LQERVLKCQW QGIMGDVFMR
LTSKESDFLD FYVSYLKELP ECLSVVSMLT TTSLKAAGLF EGDIMGDETH PSLHTLLLQP
VQRIPEYLLL LQTLLKQTDA EHPDYYLLLL CIQQFSAFTA QYAHLLQHNQ ELLLHNRKEL
KRSASDPGSD LVFWSTMKQF FKNVDCGNVM QANEMGSPYP SSNAILEHAN QVKRSKQRLL
EQIQSRRFQD WESEAHHSDS AIPFFSPDTD PRLKPPCLQS IPEIGSSERL PGKRLPPGSA
MADALGEFLL PGDAPGLEGL YEDTNSSLHN MSMFDQCSSA SSDSSIDIAF VRYPKSHQAV
REVYNRGSRE SGYKQLPGRG CVSPDEAGMM RVHHHRPLQA DQRKSKSLNG LQLDSTVSGD
SGPGHLSDHL RGNGAHQHTK LERQSSNKYH PRSSKSQSSN NSPISPPQQK AEPERQIGVT
EEELHNHHNK DSGSLPWGEE PRWKAEGNNH TPFSERSRKQ EKGGFRSSFK KLFKKK
//
