ID A0A060WS25_ONCMY Unreviewed; 547 AA.
AC A0A060WS25;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA-directed DNA polymerase family A palm domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSONMT00001533001 {ECO:0000313|EMBL:CDQ69817.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ69817.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ69817.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ69817.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FR904686; CDQ69817.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060WS25; -.
DR STRING; 8022.A0A060WS25; -.
DR PaxDb; 8022-A0A060WS25; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR040940; DNA_pol_P_Exo.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF63; DNA POLYMERASE NU; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF18049; DNA_pol_P_Exo; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 81..289
FT /note="DNA polymerase nu pseudo-exo"
FT /evidence="ECO:0000259|Pfam:PF18049"
FT DOMAIN 321..451
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|Pfam:PF00476"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 61025 MW; 3A73F7FC919F2602 CRC64;
MGERGLESTR DHSSSDTPQH RSSKTPKPPK PKRAKPGPNQ CQLTPETEPE GGSGAGDPRA
QSNQSKICLT TAMISDPRVR DAGKLSPEER GRVLEEAGQA SALVLTMVYQ DGTTQMDPEQ
KLSPSVCGVL VMLKRDLDQT GPVPGPEEGV AQRDSLVYLR LEQKPAWAQS HQDHNLDLFN
REMLLQVVSG SQLVVCYKAK DLLRTALQHY RPDLHWKQFS SCRVQDPQVA AWLLDPADPS
SCFTNLLTKH CRTPPRTPTP ALGARKVYQV ISSLSLLYQL NMELRSKLQS QGLWELYSNM
ELTMIPVLAA MESHRIHVDK ESLKTTSEML GTKMKQLEHE AHQAAGQMFL VSSSTQLRTV
LFEKLRLQER CENKKLPKTL NKQQQSTSEA VLLQLQDLHP LPKIILEYRQ VHKIKSTFVD
GVLSCMMSKN FISSTWYQTS AVTGRISAKH PVSPSSSIAG LLILSTHPFP QQCPWLNFNT
EALSFSLPLS RSLSFSLSHA LFFKRSLFLH LALCLSPSLA LSLSLSYAHT LMSDVFLLRK
ATLSCPN
//
