ID A0A060X5C3_ONCMY Unreviewed; 367 AA.
AC A0A060X5C3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Transcription elongation factor, mitochondrial {ECO:0000256|ARBA:ARBA00017000};
GN ORFNames=GSONMT00031951001 {ECO:0000313|EMBL:CDQ74763.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ74763.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ74763.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ74763.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSOMYP00000108082.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Transcription elongation factor which increases mitochondrial
CC RNA polymerase processivity. Regulates transcription of the
CC mitochondrial genome, including genes important for the oxidative
CC phosphorylation machinery. {ECO:0000256|ARBA:ARBA00025262}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC {ECO:0000256|ARBA:ARBA00004436}.
CC -!- SIMILARITY: Belongs to the TEFM family.
CC {ECO:0000256|ARBA:ARBA00009086}.
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DR EMBL; FR904998; CDQ74763.1; -; Genomic_DNA.
DR STRING; 8022.A0A060X5C3; -.
DR PaxDb; 8022-A0A060X5C3; -.
DR Ensembl; ENSOMYT00000140040.1; ENSOMYP00000108082.1; ENSOMYG00000046177.2.
DR GeneTree; ENSGT00390000010581; -.
DR OrthoDB; 5398001at2759; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR Proteomes; UP000694395; Chromosome 17.
DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006392; P:transcription elongation by mitochondrial RNA polymerase; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR039150; TEFM.
DR PANTHER; PTHR21053:SF2; TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL; 1.
DR PANTHER; PTHR21053; UNCHARACTERIZED; 1.
DR Pfam; PF12836; HHH_3; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00023271};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
SQ SEQUENCE 367 AA; 41648 MW; D1A64B0EA8C74484 CRC64;
MWVARRFMSL IARRGQYGLF YQPQGSLPKL EFRYLNCTCC WRSRIPVAGF ETLNDTLSSS
TTPCDDKSLD AYYTSEQRGV ILQLLNNAAE SELAAVKLLR GRKSVNIVEY RTRNGPFKNL
ESVTNVPLLK HKSAVIVFNS ILNPPEKKEK RKVKIQLAKF IRPEVERTWL EEANSIVSIV
CGVNKIAWAH MDRGMNVLEW KHEDCHNFLK GTYMASAYLD DISSVVSHLP TADFFVVEKT
SISLQNTALY PVMAHMRTVE AMLFALLEPR YTQPDNTAPP KVLNMMRTAV GRHFGLMVGD
SRTSGAQAMQ QMMTESVTQK IPRVTFPHNL LVKYRNSFQM GGRSRGEELC DAMLQAVAFY
ELLSESS
//
