ID A0A060XDS3_ONCMY Unreviewed; 420 AA.
AC A0A060XDS3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Transcription factor {ECO:0000256|PIRNR:PIRNR009404};
GN ORFNames=GSONMT00056053001 {ECO:0000313|EMBL:CDQ75469.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ75469.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ75469.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ75469.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR009404,
CC ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|PIRNR:PIRNR009404,
CC ECO:0000256|RuleBase:RU003796}.
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DR EMBL; FR905057; CDQ75469.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060XDS3; -.
DR STRING; 8022.A0A060XDS3; -.
DR PaxDb; 8022-A0A060XDS3; -.
DR OrthoDB; 1343784at2759; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd14458; DP_DD; 1.
DR Gene3D; 1.20.140.80; Transcription factor DP; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR038168; TF_DP_C_sf.
DR InterPro; IPR014889; Transc_factor_DP_C.
DR InterPro; IPR015648; Transcrpt_fac_DP.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR PANTHER; PTHR12548:SF4; TRANSCRIPTION FACTOR DP-1; 1.
DR Pfam; PF08781; DP; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR PIRSF; PIRSF009404; Transcription_factor_DP; 1.
DR SMART; SM01138; DP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Transcription {ECO:0000256|PIRNR:PIRNR009404,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|PIRNR:PIRNR009404,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 122..205
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 212..356
FT /note="Transcription factor DP C-terminal"
FT /evidence="ECO:0000259|SMART:SM01138"
FT REGION 88..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..420
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 46586 MW; EFFE0F0CAE933362 CRC64;
MPTKTAAEEA EEKSALVGLM ETNGELKVFI DQNRSPSKGV LSLVAVHPVS IPMAKQLLPK
TLGPSNVNIA PHMVIGTPQR PSVSSAILVN SPQTPNSQFL TQSQPADASP WSSGKRGKKG
EKNGKGLRHF SMKVCEKVQK KGVTTYNEVA DELVAEFSAA DNHISPNDSH VYDQKNIRRR
VYDALNVLMA MNIISKEKKE IKWIGLPTNS AQECQNLEVE RQRRLERIKQ KQSQLQELIL
QQIAFKNLVQ RNRQTEQQAN RPPPPNSLIH LPFIIINTSK KTVIDCSISN DKFEYLFNFD
NMFEIHDDIE VLKRMGMACG LEVGKCSPED LKVARSLVPK ALEPYVTEMA QGPISNVYIT
GGSSTNGRRH HGQGSDSGAD GPLASSSNDS HYSSSRVETP VSYMGDDDEE DDYDENDDED
//
