ID A0A060XKA1_ONCMY Unreviewed; 342 AA.
AC A0A060XKA1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Cystatin fetuin-A-type domain-containing protein {ECO:0000259|PROSITE:PS51529};
GN ORFNames=GSONMT00062425001 {ECO:0000313|EMBL:CDQ80033.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ80033.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ80033.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ80033.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; FR905534; CDQ80033.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060XKA1; -.
DR STRING; 8022.A0A060XKA1; -.
DR PaxDb; 8022-A0A060XKA1; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 2.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR025760; Cystatin_Fetuin_A.
DR InterPro; IPR046350; Cystatin_sf.
DR InterPro; IPR001363; Prot_inh_fetuin_CS.
DR PANTHER; PTHR13814:SF6; ALPHA-2-HS-GLYCOPROTEIN; 1.
DR PANTHER; PTHR13814; FETUIN; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 2.
DR SUPFAM; SSF54403; Cystatin/monellin; 2.
DR PROSITE; PS51529; CYSTATIN_FETUIN_A; 1.
DR PROSITE; PS01255; FETUIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..342
FT /note="Cystatin fetuin-A-type domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001591071"
FT DOMAIN 25..133
FT /note="Cystatin fetuin-A-type"
FT /evidence="ECO:0000259|PROSITE:PS51529"
SQ SEQUENCE 342 AA; 36146 MW; CD9590163CC6D7AB CRC64;
MSRLGIALVL GLLTGARAQL LLHNVTRPPC DSPDVKAAAL VAQDYLNGQH THGYKYALNQ
IDNIKILTKP DGSEIYLMEV DLLETTCHVL DPTPVANCTV RPKVVTAVEG DCDVVLRKVG
GVMSVTAFKC KTEESTEDLC VGCASLLPLN DTAGLAMVSA SLVTFNNRTG KESLFAIMEV
GRMSTQVVSG GARYLAEYVI VETNCTADDS DDNCVPLTNA MAQRGFCQVA GVSSLHSIQC
NIFAASSMMP IVDTNGTVPV PAPVVHVHAG NLPKVHGLRH HKLTALHDPD LSGLLSAESG
ESGESEESIV PVVPVREAPD SPAIVSAPLV PVPVCPGKKI FF
//
