ID   A0A060XU04_ONCMY        Unreviewed;       645 AA.
AC   A0A060XU04;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Fermitin family member 3a {ECO:0000313|Ensembl:ENSOMYP00000099133.1};
GN   ORFNames=GSONMT00050722001 {ECO:0000313|EMBL:CDQ83138.1};
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ83138.1, ECO:0000313|Proteomes:UP000193380};
RN   [1] {ECO:0000313|EMBL:CDQ83138.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24755649; DOI=10.1038/ncomms4657;
RA   Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA   Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA   Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA   Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA   Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA   Guiguen Y.;
RT   "The rainbow trout genome provides novel insights into evolution after
RT   whole-genome duplication in vertebrates.";
RL   Nat. Commun. 5:3657-3657(2014).
RN   [2] {ECO:0000313|EMBL:CDQ83138.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Genoscope - CEA;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSOMYP00000099133.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the kindlin family.
CC       {ECO:0000256|ARBA:ARBA00008052}.
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DR   EMBL; FR906118; CDQ83138.1; -; Genomic_DNA.
DR   STRING; 8022.A0A060XU04; -.
DR   PaxDb; 8022-A0A060XU04; -.
DR   Ensembl; ENSOMYT00000107607.2; ENSOMYP00000099133.1; ENSOMYG00000044821.2.
DR   GeneTree; ENSGT00390000013444; -.
DR   OrthoDB; 5399911at2759; -.
DR   Proteomes; UP000193380; Unassembled WGS sequence.
DR   Proteomes; UP000694395; Unplaced.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR   CDD; cd13205; FERM_C_fermitin; 1.
DR   CDD; cd17185; FERM_F1_KIND3; 1.
DR   CDD; cd01237; PH_fermitin; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR037843; Kindlin/fermitin.
DR   InterPro; IPR040790; Kindlin_2_N.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR037837; PH_Kindlin/fermitin.
DR   PANTHER; PTHR16160; FERMITIN 2-RELATED; 1.
DR   PANTHER; PTHR16160:SF1; FERMITIN FAMILY HOMOLOG 3; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF18124; Kindlin_2_N; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT   DOMAIN          345..441
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
SQ   SEQUENCE   645 AA;  73815 MW;  BF1FEEEFBA3D2946 CRC64;
     MAAWDLSVTV EELGPEAPPL KVSVTSDLHI GGVILKIVEK TQIKKDWSDH ALWWEQKQQW
     LLRPSWTLEK YEIHADARLS LTPQHKPLRL GLPNGTTLRL QACFSRPVFQ TVMGVCHLLN
     LRHPEELSLL RPMEVKKKKK DKEAEEEVVY DLTGLRTSSG PAHTLSNGMP MHFADSLQTE
     AVYKMLSVSL PAPAPETITK MPRPTSLMDK AQVHSRWLDS SRSLLQQGVQ EHDRLLLRFK
     YYCFHDLDPK YDAVRLTQLY EQARWAILLE DVDCTEEEMM LFAALQYHIG KVSLSEPQPM
     TSCPAMDDLD SALQCLEVKM EAEESITADM LETMTVAPEL QDYLKIFRPK RLTLKGYKQF
     WFAFNNTSIS YYKSKEESLK EPIQQMNLKG CEVAPDVSVA GQKFCIRLLI PGAEGMNEVY
     LRCENELQYS RWMAACRLAS KGKTLADSSF SSEVQNIQSF LAMQRTNPGA NIAQTDDSIN
     TYSLVSPRYH KKYKAKQLTP RILEAYQNVA QLPLTDALLR FLQIWQGLPD FGVSYFVVRF
     KGCRKDEVLG VTNNRLIRID LSIGDVVKTW RYNTMRQWNV NWDIQQMAIE FNGNVNIAFS
     CVTATCKIVH EYIGGYIFMA TRTKEQAEVL NQELFFKLTG GHEAI
//