ID   A0A060Y694_ONCMY        Unreviewed;       875 AA.
AC   A0A060Y694;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Phosphoinositide 3-kinase regulatory subunit 5 {ECO:0000256|ARBA:ARBA00040195};
GN   ORFNames=GSONMT00033484001 {ECO:0000313|EMBL:CDQ84690.1};
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ84690.1, ECO:0000313|Proteomes:UP000193380};
RN   [1] {ECO:0000313|EMBL:CDQ84690.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24755649; DOI=10.1038/ncomms4657;
RA   Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA   Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA   Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA   Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA   Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA   Guiguen Y.;
RT   "The rainbow trout genome provides novel insights into evolution after
RT   whole-genome duplication in vertebrates.";
RL   Nat. Commun. 5:3657-3657(2014).
RN   [2] {ECO:0000313|EMBL:CDQ84690.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Genoscope - CEA;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}. Nucleus
CC       {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; FR906523; CDQ84690.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A060Y694; -.
DR   STRING; 8022.A0A060Y694; -.
DR   PaxDb; 8022-A0A060Y694; -.
DR   Proteomes; UP000193380; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005944; C:phosphatidylinositol 3-kinase complex, class IB; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:InterPro.
DR   InterPro; IPR019522; PIK3R5/6.
DR   PANTHER; PTHR15593; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR15593:SF2; PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5; 1.
DR   Pfam; PF10486; PI3K_1B_p101; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT   REGION          398..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          566..590
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..424
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        573..590
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   875 AA;  97174 MW;  80AAFDC7A4CAB8BB CRC64;
     MQHTSCTEDR IQHALDRCLD GLRPSPTAPQ PWNVLMCSAG QSMNRWSLEE LVKRDPENFL
     ILLQQVLRKT REVQDQCQYE LVAPLAIMFS STLLQVFFWL QTPFCPPATE LLEEACEVFG
     CFLTWPEPYC SVCKGLLSTL HQELKAPGIS YHRLVREEQG LATSKHRSKT MTVLLMNPSE
     VPPEFLSVAD QLSSIQRSQR ETYVNLVKHA YQATLGTKYT LASIHKALQV KSLEELAEIF
     SMVTDVLETA AAMDDPAKGR DHVTQGLEGL RERMGVPAFN GRKSDGMLQT LPLPTAKCYM
     FHWDKDNFDI LNTILENEHD LTGFQTSSGQ EKEEGEEEFV SAMSMYNCCS VDHRASTFST
     VSSLSTASKD SMYSTLSLAS GSYAPSVLSV TSGIDSDFYE DPEDATSSPS PLERSPSSGK
     STKASARLSQ HFSRFFKTKT QSLTRAKSLG SPDAKDLVAV RSKRSNSLPQ QVHLVSPDSL
     FQTPCTPQAL KHVCFRRRPI LSSDEEGNGN STTLRVVVFG ADHVAGKVAR AYSNLRQREN
     ACPSLSRAFR LQFFFVPVKR DGVVRCPSPG GQSASPRRGS TVSTTELNNL GTEDSTNDIA
     RFIGMLDPWY ERNTLSLLSL PASVVCQQTS KIESDLYDSS YEDRLPILAD LVLYYCRHAT
     RPALMQLYQA EMTLAGGERR TEVFIHSLEL GHTAGTRAIK AMGAASKRFG IDGDREAVPL
     MLEVVYNRVV ISGRSQWTKK DKVCTSINLT KACKNPEELD SKMECLQLTM TEVLKRQNSN
     KSKKGYNQQL SVTEVKVDKV QVSGTGNTTF AVCLDQDEKK IFQGVTRCEV SVCYKPDSST
     DWRLGQGLSA QIHPLHPTFC SLLCLPIATF SGAQP
//