ID A0A060Y6R2_ONCMY Unreviewed; 444 AA.
AC A0A060Y6R2;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 08-NOV-2023, entry version 28.
DE RecName: Full=TSG101 and ALIX binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSONMT00056196001 {ECO:0000313|EMBL:CDQ85084.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ85084.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ85084.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ85084.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; FR906660; CDQ85084.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060Y6R2; -.
DR STRING; 8022.A0A060Y6R2; -.
DR PaxDb; 8022-A0A060Y6R2; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.5.990; Nemo cc2-lz domain - 1d5 darpin complex; 1.
DR InterPro; IPR032419; CC2-LZ_dom.
DR InterPro; IPR022008; EABR.
DR PANTHER; PTHR31882:SF6; TNFAIP3-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR31882; TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER; 1.
DR Pfam; PF16516; CC2-LZ; 1.
DR Pfam; PF12180; EABR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 241..273
FT /note="TSG101 and ALIX binding"
FT /evidence="ECO:0000259|Pfam:PF12180"
FT DOMAIN 317..396
FT /note="NF-kappa-B essential modulator NEMO CC2-LZ"
FT /evidence="ECO:0000259|Pfam:PF16516"
FT REGION 393..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 109..143
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 393..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 50606 MW; FC2BF944920D6D97 CRC64;
MTGIKNTMDV DLDNDTLKSK IRSCHTLTTF YHETRLEIDT LSKKIKKRDN LIADLKARLG
KYENTCINVE GYDPVVIAPA ESLLESLCKE ICKLKLKLKD TEMNAVQQAE LRQQEIQRLQ
KLLREMEREL ESVIRQSDHE KDQDIQRLRS ALAERDRAQA TRAVLCTSLA GEADQLRGQL
GATVRVCQEL LGRLEREKGG ERVTEEVKMQ QKAKEILDYT EAGRVDIRVS KLQEENQKLT
QRVAYVEGLN SKWQKYDSSR EQYVRYLCQK LNESSALAVS SSPAPGMGHM LGPRPTQEPG
PGLGLFPELA SAKAGLLQQE IARLNGLLEE KLGDCGRLGR ELDESRRRYK DRIQMLEQQV
LIYTDDFKSE RADRERAQGR IQDLQEELSR LQEQLHTQAQ SPTRDANSTC RVHKGHRISP
RMSTDSAESL LRNSANPPVT KIKN
//
