ID A0A060Y8S7_ONCMY Unreviewed; 460 AA.
AC A0A060Y8S7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Latent transforming growth factor beta binding protein 1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=GSONMT00059397001 {ECO:0000313|EMBL:CDQ88141.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ88141.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ88141.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ88141.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; FR908399; CDQ88141.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060Y8S7; -.
DR STRING; 8022.A0A060Y8S7; -.
DR PaxDb; 8022-A0A060Y8S7; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR Gene3D; 3.90.290.10; TGF-beta binding (TB) domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR017878; TB_dom.
DR InterPro; IPR036773; TB_dom_sf.
DR PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24034:SF166; VACUOLAR-SORTING RECEPTOR 1; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF07645; EGF_CA; 4.
DR Pfam; PF00683; TB; 2.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF57581; TB module/8-cys domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS51364; TB; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 70..124
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 248..302
FT /note="TB"
FT /evidence="ECO:0000259|PROSITE:PS51364"
FT DOMAIN 401..445
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CDQ88141.1"
SQ SEQUENCE 460 AA; 50784 MW; 0F10245E5B1097F6 CRC64;
CCVLPADVNE CELLSGVCGE ALCENVEGSF LCMCPDEDQE YNQMTAKCSP APTESHSSWV
KKKPSSVERK ECYYNLNDEN LCENVLTSSV TMEECCCTLG AGWGDNCEVH PCPVQGTDQF
SQMCPAGRGN VPTGDAVFGV TAAESYKDAD ECALFGQEIC KDGFCLNSPG SYECYCKTGL
YYDEVKLQCR DIDECQDESS CVGGECLNTQ GSYMCFCTRP MVLDSDNKRC VIAPEVAEQH
SVQTDYQGIC WQTVTGTRKT CTKPLANRKT TFTECCCLHG EAWGMDCALC PLKNTEDYAS
MCNVPMREGQ GRPYGRDALV AEPVQEYEVN LDYEPRPDQP GALPLYEDEE IAYDAFEGLR
AEECGILNGC ENGRCVRVQE GYTCDCFDGY TLDMSRMACV DVNECSELNN RMSLCKNAKC
INTEGSYKCV CLPGYTPSEQ PNYCVAREQE AAAAARTERE
//
