ID A0A060YH84_ONCMY Unreviewed; 810 AA.
AC A0A060YH84;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
GN ORFNames=GSONMT00013273001 {ECO:0000313|EMBL:CDQ88789.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ88789.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ88789.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ88789.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FR908954; CDQ88789.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060YH84; -.
DR STRING; 8022.A0A060YH84; -.
DR PaxDb; 8022-A0A060YH84; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR23206:SF7; ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1; 1.
DR PANTHER; PTHR23206; MASK PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00013; KH_1; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT REPEAT 30..62
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 63..95
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 463..533
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 181..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 752..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..238
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..731
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..810
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 86212 MW; 09BCEFD987D4600C CRC64;
MEAASGGYAE VGRVLLDKGA DVNAPPVPSS RDTALTIAAD KGHYKFCELL INRGAHVDVR
NKKGNTPLWL AANGGHFDVV QLLVQAGADV DAADNRKITP LMAAFRKGHV KVVQYLVKEV
NQFPSDIECM RYIATIADKE LLKKCHQCME TIVKAKDQQA AEANKNASIL LKELDLEKSR
EESKKQALAA KREKRKEKRK KKKEEQKRKQ EEEEEDEEEQ KTTQEEDEEE DGEMQKQDDS
AEEVDPPIDP PSATTTTTIG IPATFSCVFG KKRASVATTT SASRKSKKNK TKDSSPSEPI
ICQDPQQVVL AQHKANTIHG EPRGGGLTGA GGTSDSDPLD STDCASESSS SGGKSQELNF
LPDLPSSSSS SSSSSSSSSS GPTHSLLPGT EKKHCLQLHP GNQVSVSISK PTHKAPDMSE
LTPSSSVPSQ FKTMSLPVTS PNSKSLTSPK RGQKREEGWK EVVRRSKKLL VPASVVSRIM
GRGGCNITAI QDVTGAHIDV DKQKDKNGER MITIRGGTES TRHAVQLITS LIQDPAKELE
DLIPRNHFRA PGSKITSAPF PTPTGANLNL SVGAKALGSL VSSSGVSFQS SSSQTGGKMG
KGLSGVRQPF PVSLPLAYAH PQLALLAAQT MHQIRHPMLP MAQFGGTFSP AASTWRPFPV
RPPSPGSANS SPKHNGGSSG NNQATSNLSS HNDQNNTSST GSSVSSPSAS NRSPHTPGAQ
PSTPTPSSVR KQLFTSDPKH IGVNSVSMVT TTTVSSSSSH SVRGTGSPAH QHTGLTATNT
LTLFNPRSPP SLSPPSHPPA PPLLPQERRS
//
