ID   A0A060YR35_ONCMY        Unreviewed;       532 AA.
AC   A0A060YR35;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
GN   ORFNames=GSONMT00052085001 {ECO:0000313|EMBL:CDQ91929.1};
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ91929.1, ECO:0000313|Proteomes:UP000193380};
RN   [1] {ECO:0000313|EMBL:CDQ91929.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24755649; DOI=10.1038/ncomms4657;
RA   Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA   Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA   Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA   Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA   Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA   Guiguen Y.;
RT   "The rainbow trout genome provides novel insights into evolution after
RT   whole-genome duplication in vertebrates.";
RL   Nat. Commun. 5:3657-3657(2014).
RN   [2] {ECO:0000313|EMBL:CDQ91929.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Genoscope - CEA;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the formin homology family.
CC       {ECO:0000256|ARBA:ARBA00023449}.
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DR   EMBL; FR912493; CDQ91929.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A060YR35; -.
DR   STRING; 8022.A0A060YR35; -.
DR   PaxDb; 8022-A0A060YR35; -.
DR   Proteomes; UP000193380; Unassembled WGS sequence.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR043592; FMNL_animal.
DR   PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR   PANTHER; PTHR45857:SF2; FORMIN-LIKE PROTEIN 1; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT   DOMAIN          26..417
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          399..429
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        410..429
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   532 AA;  59379 MW;  68E324401522714E CRC64;
     MPPPPPGGGM PPPFGGMPDG HTGNRNKKPI QTKYRMPSLN WQALKPNQVS GTVFNELDDE
     LVLGVLNMDA FEEQFKTKAQ TAPADVGPLR AKVAQKTPSK VSLLEPNRAK NLAITLRKGG
     MAASDICTSI ETYNQEALSL DFLELLERFI PSEYEVKLIQ NYERDGRPLD ELPEEDRFMV
     RFGKIPRLPQ RISTLTFMGN FPESIQLIQP QLNAIIAASM SIKSSSKLKK ILEIILAFGN
     YMNSSKRGAA YGFRLQSLDL LLDTKSTDRR QTLLHFIVNI IQEKYPELQT FHSELYFLDK
     AALVSLDSIL QDVRALERGM EVTRKEFAIH EDNSVLQEFL TSNNDMLDSV VGDGKTAQDV
     YESAVEYFGE NPKTTPPSMF FPVFVRFIKA YKQAEQENEQ RKKQDVLSSE WKTGPLSTSP
     KPETSQKQVP MMPQMDLIAE LKRRQVTPLV REGKDGAIED IITGGPGGVR DIGSRSPVHS
     FVCVCVCVCV CVCVCERKGR GEAIQIEISE GERKRRIGKG VGNGGAILYR TG
//