ID A0A060YTI0_ONCMY Unreviewed; 422 AA.
AC A0A060YTI0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN ORFNames=GSONMT00049350001 {ECO:0000313|EMBL:CDQ92455.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ92455.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ92455.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ92455.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc
CC subfamily. {ECO:0000256|ARBA:ARBA00005530}.
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DR EMBL; FR913289; CDQ92455.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060YTI0; -.
DR STRING; 8022.A0A060YTI0; -.
DR PaxDb; 8022-A0A060YTI0; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016469; Carbohydrate_sulfotransferase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10704; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10704:SF3; CARBOHYDRATE SULFOTRANSFERASE 2; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PIRSF; PIRSF005883; Carbohydrate_sulfotransferase; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 243..395
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 422 AA; 48360 MW; 02FDBECCFC62EDB7 CRC64;
MRGKQYHRQL KLTAPWENDA GYGRKLRTHR NHTKIIAQPG IVMKVLRRKR IVLFIAYFLL
LVLTMLNLAN YKWTKVPQQC NHQMRSASYQ GRSDIRSGSS FFGELFNQHP EVFFLYEPMW
HIWQKLYPGD AVSLQGAARD MLSSLYRCDL SVFQLYNSPG GKNFTSLGLF GASLNKVVCS
YPLCSAYRKE VVGMVDDKVC KKCPPQSLRL LEEECLKYST IVIKGVRILD VNVLAPLMED
PSLDVKVVHL VRDPRAVANS RIKSRHGLIR ENLQVVRSRD PKLRRMPFVI CDRTSRTLRT
ALNPPSWLKG KYMAVRYEDL VENPVKILRN IYRFTNLTTN HDIESFALNM TSGSSSSSKP
FIVSSRNATQ AASAWRTVLS IQQIKQVEDY CHHSMVVLGY DRVRTAGEAK DLRKSLLTVS
KL
//
