ID A0A060YTW5_ONCMY Unreviewed; 355 AA.
AC A0A060YTW5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=GSONMT00055893001 {ECO:0000313|EMBL:CDQ95161.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ95161.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDQ95161.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDQ95161.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; FR919984; CDQ95161.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060YTW5; -.
DR STRING; 8022.A0A060YTW5; -.
DR PaxDb; 8022-A0A060YTW5; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041020; PH_16.
DR PANTHER; PTHR13944; AGAP007712-PA; 1.
DR PANTHER; PTHR13944:SF23; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 18; 1.
DR Pfam; PF17838; PH_16; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 73..265
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
SQ SEQUENCE 355 AA; 41376 MW; 1E70B2292CCE5D34 CRC64;
MDEPDSLRSG LKRFNEDAVS LAPSTTDSIV VEDAYYSAFR ADLESDAQDL EVESWSLAVD
QHYLKKYTKE TVKRQDVIYE LMQTEMHHVR TLKIMLRVYM RELKEHLQMD ELFPRLESLL
ELHTSFLSRL KERRRDSTQP GSDRNYNIQR LADILTTQFS GEKGDRMKEN YGDFCSHHTE
AVSYYKEQLH NNKKFQNLIR KVNNLSVVRR LGVTECILLV TQRITKYPVL VERIVQNTEV
GTEEHEELTR SLSLIKDCIV QVDAMVNLHE KASRLRDIAH KMEPKSLGKI KDGRVFHRED
LSQGRRRLLH EGTANHKAAS GRLKDIVAVL LSDVLLLLQD KDQRYVFSTV VSREF
//
