ID   A0A060YU64_ONCMY        Unreviewed;       815 AA.
AC   A0A060YU64;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN   ORFNames=GSONMT00058394001 {ECO:0000313|EMBL:CDQ95221.1};
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022 {ECO:0000313|EMBL:CDQ95221.1, ECO:0000313|Proteomes:UP000193380};
RN   [1] {ECO:0000313|EMBL:CDQ95221.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24755649; DOI=10.1038/ncomms4657;
RA   Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA   Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA   Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA   Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA   Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA   Guiguen Y.;
RT   "The rainbow trout genome provides novel insights into evolution after
RT   whole-genome duplication in vertebrates.";
RL   Nat. Commun. 5:3657-3657(2014).
RN   [2] {ECO:0000313|EMBL:CDQ95221.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Genoscope - CEA;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FR920207; CDQ95221.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A060YU64; -.
DR   STRING; 8022.A0A060YU64; -.
DR   PaxDb; 8022-A0A060YU64; -.
DR   Proteomes; UP000193380; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT   DOMAIN          185..319
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          48..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..67
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   815 AA;  92907 MW;  6FE1D3538A1D7E95 CRC64;
     MRKHFVSCLT YLLDLFQLLE ENIITFVKNE LKMFKRILSP ELPEGFESQK QDKEVVDAED
     EQQESSAREG ALKITLHVLR KMNQKELADT LEKYELAVIC QRELKSNLKK KFQCVFEGIA
     KQGNPTLLIK IYTELYITEG GTGEVNNEHE LRQIETTTRK QARPETAIKY NDIFKPLTGQ
     DKPIRTVLTK GVAGIGKTVS VQKFILDWAE GNANQDVQFV FSFPFRELNL MKEDKHTFIE
     LLNHFSMETK QSRISNYNKY KVLFIFDGLD ECRLPLDFQK NKICCDITES TSVDVLLTNL
     IKGNLLPSAL FWITTRPAAA NKIPSGCVDQ VTEVRGFNDS QKEEYFRKRF SDEDLASRII
     SHIKTSRSLH IMCHIPVFCW ISATVLEHML KHKREEMPKT LTEMYTHLVM FYTKQKNEKY
     PGKEETGPHW NKESILSLGK LAFQQLVKGN LIFYEGDLKE AGIDVNEASV YSGLCTQLFK
     EECGLYQDKV YCFVHLSIQE FLAAVYVFLS FNNNNENLMD EPQSTSRNFS VRIKQRRKVT
     FYKSAVDKAL QSETGNLDLF LRFLLGLSLE SNQKHLRGLL TNSRSSSKTH EKTVKYIKEK
     IRENPSPERS INLFHCLNEL NDHSLVKEIQ SYLRSGSLSK PKLSPAQWSA LVFVLLTSEK
     ELDVFDLKKY SRSEEGLLRL LPVVKASRAA LLSGCGVTEE GCASLVSALR SNPSHLRELD
     LSNNDLKDSG VKLLSAGLGN PHCKLETLRL CFSGLSFNVK PLTPERAGPE LQSPRRLRGQ
     TALCWTGGST LQTGETQVCR GFILMFISDM FDSSG
//