ID A0A060ZFC7_ONCMY Unreviewed; 252 AA.
AC A0A060ZFC7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Ras-GEF domain-containing protein {ECO:0000259|PROSITE:PS50009};
DE Flags: Fragment;
GN ORFNames=GSONMT00043923001 {ECO:0000313|EMBL:CDR00319.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CDR00319.1, ECO:0000313|Proteomes:UP000193380};
RN [1] {ECO:0000313|EMBL:CDR00319.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [2] {ECO:0000313|EMBL:CDR00319.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FR955902; CDR00319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A060ZFC7; -.
DR STRING; 8022.A0A060ZFC7; -.
DR PaxDb; 8022-A0A060ZFC7; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF175; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380}.
FT DOMAIN 102..252
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CDR00319.1"
SQ SEQUENCE 252 AA; 28656 MW; 5D5A2DA07E5DE8DC CRC64;
VCVVYCSDHT YTTIRVAVAA TGREVTSAVA DKLASNDDLL LVHLSSAGEK QMLKPNDVSV
FSTLSINGRM FACPRDQLNA LTPLPDQEGP SAGSMSSFEL MSSKDLAYQM TLYDWELFSC
VHEHELLYHT FGRQSFRRTT ANLDLFLRRF NQVQLWVVTE VCLCGQLSKR VQLLKKFIKI
AAHCREFKNL NSFFAIIMGM SNPAVSRLTQ TWEKLPSKFK KFYAEFESMM VSCSSKNNFL
LTPKWTIKLL TF
//
