ID A0A061A9Z9_9MOLU Unreviewed; 402 AA.
AC A0A061A9Z9;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=3-ketoacyl-CoA thiolase {ECO:0000313|EMBL:CDR30720.1};
GN Name=fadI {ECO:0000313|EMBL:CDR30720.1};
GN ORFNames=Aocu_06470 {ECO:0000313|EMBL:CDR30720.1};
OS Acholeplasma oculi.
OC Bacteria; Mycoplasmatota; Mollicutes; Acholeplasmatales;
OC Acholeplasmataceae; Acholeplasma.
OX NCBI_TaxID=35623 {ECO:0000313|EMBL:CDR30720.1, ECO:0000313|Proteomes:UP000032434};
RN [1] {ECO:0000313|Proteomes:UP000032434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kube M.;
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; LK028559; CDR30720.1; -; Genomic_DNA.
DR RefSeq; WP_045749235.1; NZ_UFRU01000001.1.
DR AlphaFoldDB; A0A061A9Z9; -.
DR STRING; 35623.Aocu_06470; -.
DR KEGG; aoc:Aocu_06470; -.
DR PATRIC; fig|35623.3.peg.647; -.
DR HOGENOM; CLU_031026_0_0_14; -.
DR InParanoid; A0A061A9Z9; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000032434; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000032434};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 4..263
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 271..400
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 357
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 388
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 402 AA; 42909 MW; 3FD2C3C44862FDBB CRC64;
MKKVYVVAAN RSPIGSFLGT LSKISPAEFG AQVLSKMLAK HQIDPSIIDE VIIGNVLPAG
QKQGLARQVS ILSGIHESVP AYSVNMICGS GMKSVINAFS NIQAGIADVV VAGGVESMSQ
APFLVDGSIR QGVKMGNMNL VDYMLTDGLT DAFGNYHMGI TAENIVEKHQ FTRQMQDEFA
YNSQLKAREA LKQGKFKEEI IPIVIKDRKG EIVFSEDEYI NHTTTLEKIA ALKPAFKKDG
TVTAASSSGI NDGASFIVIA SEDAIKKHHL TPLFEVIGVG QAGVDPSVMG LGPVPAIEKS
LVFAGIRIQD IDIFELNEAF AAQALGVVRE VSEKYQVTED SILDKTNPNG GAIALGHPVG
ASGNRIMVTL MHEMLRNKDQ KIGLASLCIG GGMGTSVILR KV
//
