ID A0A061D7S3_BABBI Unreviewed; 336 AA.
AC A0A061D7S3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT, putative {ECO:0000313|EMBL:CDR96593.1};
GN ORFNames=BBBOND_0304960 {ECO:0000313|EMBL:CDR96593.1};
OS Babesia bigemina.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5866 {ECO:0000313|EMBL:CDR96593.1, ECO:0000313|Proteomes:UP000033188};
RN [1] {ECO:0000313|Proteomes:UP000033188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bond {ECO:0000313|Proteomes:UP000033188};
RX PubMed=24799432; DOI=10.1093/nar/gku322;
RA Jackson A.P., Otto T.D., Darby A., Ramaprasad A., Xia D., Echaide I.E.,
RA Farber M., Gahlot S., Gamble J., Gupta D., Gupta Y., Jackson L.,
RA Malandrin L., Malas T.B., Moussa E., Nair M., Reid AJ., Sanders M.,
RA Sharma J., Tracey A., Quail M.A., Weir W., Wastling J.M., Hall N.,
RA Willadsen P., Lingelbach K., Shiels B., Tait A., Berriman M., Allred D.R.,
RA Pain A.;
RT "The evolutionary dynamics of variant antigen genes in Babesia reveal a
RT history of genomic innovation underlying host-parasite interaction.";
RL Nucleic Acids Res. 42:7113-7131(2014).
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000256|ARBA:ARBA00005378}.
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DR EMBL; LK391709; CDR96593.1; -; Genomic_DNA.
DR RefSeq; XP_012768779.1; XM_012913325.1.
DR AlphaFoldDB; A0A061D7S3; -.
DR STRING; 5866.A0A061D7S3; -.
DR EnsemblProtists; CDR96593; CDR96593; BBBOND_0304960.
DR GeneID; 24565134; -.
DR KEGG; bbig:BBBOND_0304960; -.
DR VEuPathDB; PiroplasmaDB:BBBOND_0304960; -.
DR OMA; IGPIYSR; -.
DR OrthoDB; 275853at2759; -.
DR Proteomes; UP000033188; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013748; Rep_factorC_C.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF20; REPLICATION FACTOR C SUBUNIT 4; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000033188}.
FT DOMAIN 37..173
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 336 AA; 37788 MW; 6488F406CB93868F CRC64;
MKKNAPWVEK YRPAKLADVV FQTHAVATMQ QIVETFNMPH MIFHGPPGTG KTSAALAMAR
QIYGVEGMKE RVLELNASDE RGISVVRERI KTYTRLNISN NRINPETGRV MPNFKIIILD
EADMITPDAQ AALRRVIENF SNISRFILIC NYLHKIIGPI YSRCSAFHFK PIVQEAQVER
LRFICQSEQL ECDDAALDFL TRVSQGDMRR SVTLLQSTAS LYSKVTEDAV RNVSGYPPRH
IVEDIFTACM APTNEVEAIC KQIVHDGWEI AAIFQQLAEY VVNCETLSDV QKAMITIELS
GRDFALLQGG LQYFQLASIC FHIRSVIANG GQRASA
//
