ID A0A061D7S4_BABBI Unreviewed; 491 AA.
AC A0A061D7S4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Methyltransferase, putative {ECO:0000313|EMBL:CDR93765.1};
GN ORFNames=BBBOND_0100940 {ECO:0000313|EMBL:CDR93765.1};
OS Babesia bigemina.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5866 {ECO:0000313|EMBL:CDR93765.1, ECO:0000313|Proteomes:UP000033188};
RN [1] {ECO:0000313|Proteomes:UP000033188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bond {ECO:0000313|Proteomes:UP000033188};
RX PubMed=24799432; DOI=10.1093/nar/gku322;
RA Jackson A.P., Otto T.D., Darby A., Ramaprasad A., Xia D., Echaide I.E.,
RA Farber M., Gahlot S., Gamble J., Gupta D., Gupta Y., Jackson L.,
RA Malandrin L., Malas T.B., Moussa E., Nair M., Reid AJ., Sanders M.,
RA Sharma J., Tracey A., Quail M.A., Weir W., Wastling J.M., Hall N.,
RA Willadsen P., Lingelbach K., Shiels B., Tait A., Berriman M., Allred D.R.,
RA Pain A.;
RT "The evolutionary dynamics of variant antigen genes in Babesia reveal a
RT history of genomic innovation underlying host-parasite interaction.";
RL Nucleic Acids Res. 42:7113-7131(2014).
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DR EMBL; LK391707; CDR93765.1; -; Genomic_DNA.
DR RefSeq; XP_012765951.1; XM_012910497.1.
DR AlphaFoldDB; A0A061D7S4; -.
DR STRING; 5866.A0A061D7S4; -.
DR EnsemblProtists; CDR93765; CDR93765; BBBOND_0100940.
DR GeneID; 24562306; -.
DR KEGG; bbig:BBBOND_0100940; -.
DR VEuPathDB; PiroplasmaDB:BBBOND_0100940; -.
DR OMA; IQNKHYE; -.
DR OrthoDB; 450395at2759; -.
DR Proteomes; UP000033188; Chromosome 1.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Methyltransferase {ECO:0000313|EMBL:CDR93765.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033188};
KW Transferase {ECO:0000313|EMBL:CDR93765.1}.
FT REPEAT 85..117
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 491 AA; 55000 MW; FDD2020508B20844 CRC64;
MDNEPMDADM SDEDIDYDEE WLYCLRANEL DDAVKLLKQR LVTNIHVVDN NGNGPLHYCC
ANNLAEAVVF LLTECKMGYC RPNHSGNTPL QWAVQTNSAD AVKQLLLHDY RVHRADYEKL
ERSDFFENVE SVVLSDAHRL DDDTKRHYNI TEYPSNYAAN NWVGIVTPNS FGKSILNDAF
SAKDQTILHA ILEHPASAVL DKPTETSQTD LPIERVSVGG VNGVVHAFQF GGRIADNRPP
VVRARELEIK QDEILNAQSA EMDHTGEVIW ETDLVAAQWL TALARDGKFE GKRVLQLGSG
CGLSAIAMYV SAAFYQKAPH TLVFTDVCSD TVRNLKFNVE LNKLGADDRV RIHYLDWTKP
DTWPRDEQGS LQTFDIVIGS DLVYDANLVE PLTNVIQATL SKAHGEVFYA FKQARDGARL
IPEALTKLGF NVTTQPSPRE FQSNPLESSN DKVLEAFFPD LQDDDYTLLY ATRGNACTSD
AAVHNDPVYR N
//
