ID A0A061DBF6_BABBI Unreviewed; 204 AA.
AC A0A061DBF6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};
GN ORFNames=BBBOND_0405200 {ECO:0000313|EMBL:CDR98036.1};
OS Babesia bigemina.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5866 {ECO:0000313|EMBL:CDR98036.1, ECO:0000313|Proteomes:UP000033188};
RN [1] {ECO:0000313|Proteomes:UP000033188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bond {ECO:0000313|Proteomes:UP000033188};
RX PubMed=24799432; DOI=10.1093/nar/gku322;
RA Jackson A.P., Otto T.D., Darby A., Ramaprasad A., Xia D., Echaide I.E.,
RA Farber M., Gahlot S., Gamble J., Gupta D., Gupta Y., Jackson L.,
RA Malandrin L., Malas T.B., Moussa E., Nair M., Reid AJ., Sanders M.,
RA Sharma J., Tracey A., Quail M.A., Weir W., Wastling J.M., Hall N.,
RA Willadsen P., Lingelbach K., Shiels B., Tait A., Berriman M., Allred D.R.,
RA Pain A.;
RT "The evolutionary dynamics of variant antigen genes in Babesia reveal a
RT history of genomic innovation underlying host-parasite interaction.";
RL Nucleic Acids Res. 42:7113-7131(2014).
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000256|ARBA:ARBA00003357, ECO:0000256|RuleBase:RU364033}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364033}.
CC -!- SIMILARITY: Belongs to the ELOF1 family.
CC {ECO:0000256|ARBA:ARBA00009730, ECO:0000256|RuleBase:RU364033}.
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DR EMBL; LK391711; CDR98036.1; -; Genomic_DNA.
DR RefSeq; XP_012770222.1; XM_012914768.1.
DR AlphaFoldDB; A0A061DBF6; -.
DR STRING; 5866.A0A061DBF6; -.
DR EnsemblProtists; CDR98036; CDR98036; BBBOND_0405200.
DR GeneID; 24566577; -.
DR KEGG; bbig:BBBOND_0405200; -.
DR VEuPathDB; PiroplasmaDB:BBBOND_0405200; -.
DR OrthoDB; 276470at2759; -.
DR Proteomes; UP000033188; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934:SF0; TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR20934; UNCHARACTERIZED; 1.
DR Pfam; PF05129; Elf1; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU364033};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364033};
KW Reference proteome {ECO:0000313|Proteomes:UP000033188};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364033};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364033};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU364033};
KW Zinc-finger {ECO:0000256|RuleBase:RU364033}.
FT REGION 86..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 204 AA; 22376 MW; 5FCD18C0803F9F38 CRC64;
MAKRKTKKVQ LSRAQLMQKR RGKLDKEFLC YYCQHEKSVA IKIDNQSGVG FLSCRICGVK
FSTRVTVLDE AVDVYALWMD SCREGQRSDT LPPKKNSVDT PSTQGTIQGK TVATKAQAEN
EAPRADISTP AADDATPEDA VKRSREEDST TKSFSIDPEL ASAAFSAIGG GKRSKRIIDA
VEETPDETEY AVGTLTGDNL FEDD
//
