ID   A0A061DMS9_THECC        Unreviewed;       529 AA.
AC   A0A061DMS9;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:EOX91268.1};
GN   ORFNames=TCM_000514 {ECO:0000313|EMBL:EOX91268.1};
OS   Theobroma cacao (Cacao) (Cocoa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX   NCBI_TaxID=3641 {ECO:0000313|EMBL:EOX91268.1, ECO:0000313|Proteomes:UP000026915};
RN   [1] {ECO:0000313|EMBL:EOX91268.1, ECO:0000313|Proteomes:UP000026915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX   PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA   Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA   Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA   Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA   Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA   Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA   Kuhn D.N.;
RT   "The genome sequence of the most widely cultivated cacao type and its use
RT   to identify candidate genes regulating pod color.";
RL   Genome Biol. 14:R53.1-R53.24(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; CM001879; EOX91268.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061DMS9; -.
DR   EnsemblPlants; EOX91268; EOX91268; TCM_000514.
DR   Gramene; EOX91268; EOX91268; TCM_000514.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_0_1; -.
DR   InParanoid; A0A061DMS9; -.
DR   OMA; QYLFSIC; -.
DR   Proteomes; UP000026915; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd20654; CYP82; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR47947:SF29; (RAPE) HYPOTHETICAL PROTEIN; 1.
DR   PANTHER; PTHR47947; CYTOCHROME P450 82C3-RELATED; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW   ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   529 AA;  59867 MW;  46695BD8DBFC2FC8 CRC64;
     MDPFLQHLFT TVCSLVALLS CIYFYQSKKA STHGKRCCTP PQAGGALPVI GHMHLLGGQQ
     LTHKTLGAMA DKYGPVFSIR LGSHRVLVLN SWEMAKECFT VHDKVFSTRP SIAASKHLGY
     DFAMFGFAPY GSYWREMRKI ATIELLSSHR IDMLKHIRAS EVKTAIRELY KSWLSKGSAE
     TEVFVDMKQW FGDLTHNIAL RMVGGRRYFG PNADCEEADA RRCQKVMRDF VYLFGVFVLS
     DAIPFLGWLD FQGYEKSMKR TAKQLDSLVE RWLEEHKQKR LSGGGVIEEQ DFMDVMLNIL
     EDGKITGFDA DTINKATCLN LILAGSDTTM VTLTWALSLL LNNPRVLKRA QDELDMHVGK
     DRPLEESDIS NLVYLQSIVK ETLRLYPPSP IIGLRAALED CTLSTGYHIP SGTRLMVNAW
     KIQRDERVWP DPHDFQPERF LTSHKDMDFR GQTFELIPFG SGRRSCPGTS LALKMVHFIL
     GRFLHSFDVA KPSKLEDVDM TESAGLTNLK ATPLEVLVTP RLNSQLYVV
//