ID A0A061E0N8_THECC Unreviewed; 820 AA.
AC A0A061E0N8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN ORFNames=TCM_006818 {ECO:0000313|EMBL:EOX97906.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOX97906.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOX97906.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR EMBL; CM001880; EOX97906.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061E0N8; -.
DR EnsemblPlants; EOX97906; EOX97906; TCM_006818.
DR Gramene; EOX97906; EOX97906; TCM_006818.
DR HOGENOM; CLU_005230_0_0_1; -.
DR Proteomes; UP000026915; Chromosome 2.
DR GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR PANTHER; PTHR11629:SF112; V-TYPE PROTON ATPASE SUBUNIT A3; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
DR PIRSF; PIRSF001293; ATP6V0A1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 423..447
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 468..485
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 548..566
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 578..601
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 637..655
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 757..778
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT REGION 671..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 101..128
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 820 AA; 92932 MW; 0428C22AC8F08346 CRC64;
MGDVRGGCCP PMDLFRSEPM QLVQLIIPIE SAHLTVAYLG DLGILQFKDL NSEKSPFQRT
YAAQIKKCGE MARKMRFFKE QMVKAGFSPS TKSEARGDID VDDLEVKLGE LEAELIEMNA
NGEKLQRSYN ELVEYKLVLQ KAGEFFASAQ HSAVAQQREM ESRQMGEESI ETPLLQDQET
TIDLSKQVKL GFITGLVPRE KSMAFERILF RATRGNVLLK QVPVEDPVTD PVSGEKMEKN
VFVVFYSGER AKNKILKICE AFGANRYPFA EDLGKQALMI TEVSGRITEL KTTIDAGSYH
RDNLLRTIGD QFEQWNLKVK KEKSIYHTLN MLSLDVTKKC LVAEGWSPVF ATKQVQESLQ
RAAFDSNSQV GAIFQVLSTR ESPPTYFRTN KFTSAFQEIV DAYGVAKYQE ANPGVYTIIT
FPFLFAVMFG DWGHGICLLL ATLFFIVREK KLSSQKLGDI TEMTFGGRYV IMMMALFSIY
TGLIYNEFFS VPFELFGRSA YACRDLTCRD ASTVGLIKVR ETYPFGVDPA WHGTRSELPF
LNSLKMKMSI LLGVAQMNLG IILSYFNATF FGSSLNVWFQ FIPQMIFLNS LFGYLSLLII
VKWCTGSQAD LYHVMIYMFL SPTDELGENQ LFPGQKTVQL VLLLLALVSV PWMLLPRPFL
LKKQHENHQG QSYTPLESTD DTLHSEANND SHGHGHEEFE FSEVFVHQLI HTIEFVLGAV
SNTASYLRLW ALSLAHSELS VVFYEKVLLL AWGFNNIIIL IVGIIIFIFA TVGVLLVMET
LSAFLHALRL HWVEFQNKFY EGDGYKFYPF SFALLGDEDD
//
