ID A0A061E457_THECC Unreviewed; 1029 AA.
AC A0A061E457;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=TCM_008737 {ECO:0000313|EMBL:EOX99799.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOX99799.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOX99799.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
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DR EMBL; CM001880; EOX99799.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061E457; -.
DR STRING; 3641.A0A061E457; -.
DR EnsemblPlants; EOX99799; EOX99799; TCM_008737.
DR Gramene; EOX99799; EOX99799; TCM_008737.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_000445_16_2_1; -.
DR InParanoid; A0A061E457; -.
DR OMA; ATHEKCL; -.
DR Proteomes; UP000026915; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0010033; P:response to organic substance; IEA:UniProt.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd06223; PRTases_typeI; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 6.10.250.1190; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43719:SF73; HISTIDINE KINASE 3; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EOX99799.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 157..383
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 451..715
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 743..865
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 891..1028
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 941
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1029 AA; 115251 MW; 56B5A561FB9A80C0 CRC64;
MSLLHVFGFG LKVGHLLWML CCWIASMISM NWFINGEFKD AKAGLLGDSG SKMWFKCWDK
ISSYSFKIHH HYYQYIGSKR LGKTWWRKLL FSWVIVWTIA SIWIFCYMSS QATEKRKETL
ASMCDERARM LQDQFNVSMN HIQAMSILIS TFHHGKHPSA IDQRTFARYT ERTAFERPLT
SGVAYAVRVL HSEREQFEKQ QGWTIKRMDT LEKNPVHKDD YNPDLLEPSP IQEEYAPVIF
AQDIISHVVS IDMLSGKEDR ENVLRARKSG KGVLTAPFRL LKTNRLGVIL TFAVYKGDLP
SNATPNERIQ ATDGYLGGVF DIESLVEKLL QQLASKQTIL VNVLDTTNQS HPISMYGSNA
SDDGLEHVSH LNFGDPFRKH EMRCRFKQKP PWPWLAITTS IGILVIALLV GHIFHATVNR
IAKVEDDFHE MMELKKKAEA ADVAKSQFLA TVSHEIRTPM NGVLGMLHML MDTDLDVTQL
DYVRTAQASG KALVALINEV LDQAKIESGK LELEEVQFDL RAVLDDVLSL FSGKSQDKGV
ELAVYISDRV PEMLIGDPGR FRQIITNLMG NSIKFTEKGH ILVTVHLVEE VIDSIEVETE
SSSKNTLSGF PVADRCVSWK GFRTFSQEGS MQPFSDSINL IVSVEDTGEG IPLEAQSRVF
TRFMQVGPSI SRTHGGTGIG LSISKCLVGL MKGEIGFVSI PKIGSTFTFT AVFTGGCSSS
NEYKSQQINK QSNSVSSEFH GMRALLVDTR PVRAKVSRYH IQRLGIHVEV ASDWNQGLSS
ISRGNNAIHM VLIEQEVWDR DLNSSALFIS SLEKIDHGTP PKAFLLSNSI SSSRANTTTS
GVCNLTVIPK PLRASMLAAS LQRAMGVGNK GNPRNGELPS LSLRNLLLGR KILIVDDNNV
NLKVAAGALK KYGADVISAA RGIEAIELLT PPHQFDACFM DIQMPEMDGF EATKKIRDME
QNINNRIQFG ELSVKTYNNV FNWHVPILAM TADVIQATHE ECLRCGMDGY VSKPFEAEQL
YREVSRFFQ
//
