ID A0A061E5L8_THECC Unreviewed; 778 AA.
AC A0A061E5L8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Formin-like protein {ECO:0000256|RuleBase:RU361260};
GN ORFNames=TCM_010137 {ECO:0000313|EMBL:EOY00305.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY00305.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY00305.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
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DR EMBL; CM001880; EOY00305.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061E5L8; -.
DR STRING; 3641.A0A061E5L8; -.
DR EnsemblPlants; EOY00305; EOY00305; TCM_010137.
DR Gramene; EOY00305; EOY00305; TCM_010137.
DR eggNOG; KOG1922; Eukaryota.
DR HOGENOM; CLU_007699_3_0_1; -.
DR InParanoid; A0A061E5L8; -.
DR OMA; TSHMNIF; -.
DR Proteomes; UP000026915; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF354; FORMIN-LIKE PROTEIN 4; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 307..744
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 37..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 661..688
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 37..70
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..197
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..752
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 84801 MW; C9A60F1F5CBA94FA CRC64;
MAVKFQTLVF LNLVIVSFIS VLPFSYSQGS PQNIEVFYPY QPPPPDPEAS SPKPSNSLPS
PEPPPPSPSS SSNDTNKTIA KAVAATAAST IVIAGIFFFF IRKYVLAQRK TDRVGDSSQG
GQPGVPPDEF ERVNGNIKGL IVDENGLDVL YWRQLQDGEN INGFRKGILR SPKDEEEGRG
GMVRKGSRSK KAEPVQEIPL LRGKSSTSQV PPPEDDDSSE IIAPPLPIQN NTNNSQVTPP
PPPPPPPQPA PPNRTPAPPP PPVPAKRPAP PPPPPKTGDS ATSLKPPPAA RDKSGGGKPG
EASGDGATEN GNNQVKLKPL HWDKVNKNVE HSMVWDKING GSFKFDDDLM EALFGYVATS
RKSPTSSSNS KNARSTDTSS SSQIMVLDAR KSQNVAIVLK SLALSRRELL EALNEGQGLE
ADTVEKLIRI APTEEEQSQI LNFNGDPTRL ADAESFLFHI LKAIPSAFTR LNAMQFRSNY
DLEILHMKES LQTLELGCKE LRSQRLFMRL LEAILKAGNR MNAGTARGNA QAFNLTSLLK
LSDVKSTDGK TTLLHFVVEE VVRSEGKKCF ISRSRSLSRN SSRSSNSSSD HSTPKEDREK
EYVTLGLPVV GGLSAEFTNV KKAATIDFNT FTGTCSSLTA RMAEIKQLVL QCMADGKGGF
AKEMKGFIDD AEEELKVIRE EQNRVMDLVK KTTEYYQAGA KKDPFQIFVI VRDFLGMVDQ
ACVEIARNQQ RRKSSTGSYG SRSPNSQESR TKMRFPILPA SFMTGKSGSN SSDSDVDS
//
