ID   A0A061EQ48_THECC        Unreviewed;       693 AA.
AC   A0A061EQ48;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Cullin 1 isoform 3 {ECO:0000313|EMBL:EOY06477.1};
GN   ORFNames=TCM_021183 {ECO:0000313|EMBL:EOY06477.1};
OS   Theobroma cacao (Cacao) (Cocoa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX   NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY06477.1, ECO:0000313|Proteomes:UP000026915};
RN   [1] {ECO:0000313|EMBL:EOY06477.1, ECO:0000313|Proteomes:UP000026915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX   PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA   Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA   Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA   Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA   Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA   Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA   Kuhn D.N.;
RT   "The genome sequence of the most widely cultivated cacao type and its use
RT   to identify candidate genes regulating pod color.";
RL   Genome Biol. 14:R53.1-R53.24(2013).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; CM001882; EOY06477.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061EQ48; -.
DR   EnsemblPlants; EOY06477; EOY06477; TCM_021183.
DR   Gramene; EOY06477; EOY06477; TCM_021183.
DR   HOGENOM; CLU_004747_3_0_1; -.
DR   Proteomes; UP000026915; Chromosome 4.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          338..568
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   693 AA;  80641 MW;  C0151F1B62700EDB CRC64;
     MCTQKPPHDY SQQLYDKYRE SFEEYITSTV LPSLREKHDE FMLRELVKRW ANHKVMVRWL
     SRFFHYLDRY FIARRSLPPL NEVGLTCFRE LVYQELNAKV RDAVISLIDQ EREGEQIDRA
     LLKNVLDIFV EIGMGQMDYY ENDFEATMLK DTAAYYSRKA SNWILEDSCP DYMLKAEECL
     KREKDRVSHY LHSSSEPKLL EKVQHELLSV NANLLLEKEH SGCHALLRDD KVEDLSRMFR
     LFCKIPRGLD PVSGIFKQHV TAEGTALVKQ AEDAASNKKA DKKDVVGMQE QVFVRKVIEL
     HDKYLAYVND CFQNHTLFHK ALKEAFEVFC NKGVAGSSSA ELLATFCDNI LKKGGSEKLS
     DEAIEETLEK VVKLLAYISD KDLFAEFYRK KLARRLLFDK SANDDHERSI LTKLKQQCGG
     QFTSKMEGMV TDLTLARENQ TSFDEYLSNN PNANPGIDLT VTVLTTGFWP SYKSFDLNLP
     AEMIKCVEVF RDFYQTKTKH RKLTWIYSLG TCNLIGKFEP KTMELIVTTY QASALLLFNS
     SDRLSYSEIM TQLNLTDDDV VRLLHSLSCA KYKILNKEPS TKTISPTDYF EFNSKFTDKM
     RRIKIPLPPV DEKKKVIEDV DKDRRYAIDA SIVRIMKSRK VLGHQQLVME CVEQLGRMFK
     PDFKAIKKRI EDLITRDYLE RDKDNPNTFR YLA
//