ID A0A061ETN9_THECC Unreviewed; 1460 AA.
AC A0A061ETN9;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Pleiotropic drug resistance 11 isoform 1 {ECO:0000313|EMBL:EOY08161.1};
GN ORFNames=TCM_022498 {ECO:0000313|EMBL:EOY08161.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY08161.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY08161.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; CM001883; EOY08161.1; -; Genomic_DNA.
DR EnsemblPlants; EOY08161; EOY08161; TCM_022498.
DR Gramene; EOY08161; EOY08161; TCM_022498.
DR eggNOG; KOG0065; Eukaryota.
DR InParanoid; A0A061ETN9; -.
DR OMA; MPRFVTQ; -.
DR Proteomes; UP000026915; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR PANTHER; PTHR48040:SF42; ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48040; PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 540..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..599
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 684..706
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 769..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1205..1223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1235..1263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1283..1306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1318..1342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1348..1367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1379..1398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1429..1452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 171..444
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 859..1112
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1460 AA; 165268 MW; 2C57711EA56C24AD CRC64;
MASALAGDDL ARSMSSRRSW AASGSHRSWA SASFREVWQP PPEVFNRSGR QDDEEELRWA
AIERLPTYDR LRKGMLRQVL DNGRIVHDEV DVTKLGLQDK KQLMDSMLKV VEEDNERFLR
RLRDRTDRVG IEIPKIEVRF EHLAVEGDVY VGSRALPTLL NVTLNTIESI LGLVRLAPSK
KRKIQILKDV SGIVKPSRMT LLLGPPGAGK TTLLLALAGK LDRDLRSSGK VTYCGHELNE
FVPQRTCAYI GQHDLHYGEM TVRETLDFSG RCLGVGTRYE MLSELSRREK EAGIKPDSEI
DAFMKATALA GQETSLVTDY ILKILGLDIC ADIMVGDEMR RGISGGQKKR VTTGEMLVGP
AKALFMDEIS TGLDSSTTFQ ICKFMRQMVH IMDVTMVISL LQPAPETYDL FDDIIVLSEG
LIVYQGPREN VLDFFEYMGF KCPERKGVAD FLQEVTSKKD QEQYWFKKNQ PYRYVSSSDF
VHGFSSFHIG QQLASDLRVP YDKSRTHPAA LVTEKYGISN WELFRACFAR EWLLMKRNSF
VYIFKTVQIT IMSLIALTVY LRTEMPVGTL EDGQKFFGAL FFSLINVMFN GMAELAMTVF
RLPVFYKQRD FLFYPAWAFG LPIWVLRIPL SLMESGIWIA LTYYTIGFAP AASRFFRQFL
AFFGIHQMAL SLFRFIAAVG RTQVVANTLG TFTLLLVFVL GGFIVAKDDI EPWMIWGYYV
SPMMYGQNAI VMNEFLDARW SAKNNDTRIN APTVGKVLLK TRGFFTEDYW FWICVGALFA
FSLVFNILFI GALTFLNPLG DSKAVVVNDN ENNKTKNPYS AGRRPEGTNQ QVRNSSDIVG
AAGHAPRKGM VLPFQPLSLA FNHINYYVDM PAEMKTQGIE EDRLQLLRDV SGAFRPGILT
ALVGVSGAGK TTLMDVLAGR KTGGYIEGNI SISGYTKNQA TFARVSGYCE QNDIHSPNVT
VYESLLYSAW LRLSSDIDTK TRKMFVDEVM ELVELKPLRN ALVGLPGVDG LSTEQRKRLT
IAVELVANPS IIFMDEPTSG LDARAAAIVM RTVRNTVDTG RTVVCTIHQP SIDIFEAFDE
LLLMKRGGQV IYAGPLGRHS HKLIEYFEAV QGVQKIRDGH NPATWMLEVS APPVEAQLNV
DFADIYANSS LYRRNQELIK ELSAPAPGSK DLFFPTKYSQ PFLTQCKACF WKQHWSYWRN
PQYNAIRFFL TIFIGILFGL IFWNKGEQTT KQQDLMNLLG AMYSAVLFLG ATNASAVQSV
VAIERTVFYR ERAAGMYSEL PYAFAQVAIE TIYTAIQTII YTLLLYSMIG FEWKVGKFLW
FYYYILTCFV YFTLYGMMVV ALTPGHQIAA IVMSFFLSFW NLFSGFLIPR TQIPVWWRWY
YWASPVAWTL YGLVTSQVGD KNALVEVPGQ GDISVKDFLK GTLGFEYDFL PAVAAAHIGW
CLLFFFVFAY GIKFLNFQRR
//
