ID A0A061FCW4_THECC Unreviewed; 751 AA.
AC A0A061FCW4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN ORFNames=TCM_034141 {ECO:0000313|EMBL:EOY14901.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY14901.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY14901.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR EMBL; CM001886; EOY14901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061FCW4; -.
DR EnsemblPlants; EOY14901; EOY14901; TCM_034141.
DR Gramene; EOY14901; EOY14901; TCM_034141.
DR Proteomes; UP000026915; Chromosome 8.
DR GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
DR PIRSF; PIRSF001293; ATP6V0A1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 421..445
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 466..483
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 546..564
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 576..599
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 635..653
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT COILED 92..133
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 751 AA; 85334 MW; DDD618B7EEF1AF40 CRC64;
MGEGRQRPTM DLLRSEPMQL VQLIIPIESA HRSISYLGDL GLFQFKDLNS EKSPFQRTYA
TQIKRSGEMA RKLRFFKEQM TKAGLSPSTR SARNDDVDLD NLEVKLGELE AELIEMNANH
EKLQQSYNEL KEYKLVMQKA GEFFQSAQSS AAAKQREAEA EQRGEGSIDS PLLLEQEMVT
DPSKQVKLGF VSGLVSRERS LAFERILFRA TRGNVFLKQS VVEDPVTDPA SGEKVEKNVF
IVFYSGERAR NKIMKICEVF GANRYPFTED LGKQFQIITE VSGRLEELKT TIDVGLVHQS
NLLQTIAYHF ENWSLLVKKE KSIYHTLNML SIDVSRKCLV AEGWCPVFAT NQIQNVLQKA
TIDSSSQVGT IFHVLQTKES PPTYFHTNKF TSAFQEIVDA YGIAKYQEAN PAVFTIITFP
FLFAVMFGDW GHGICLCLAT SYFIIREKKF SSQKLGDITE MIFGGRYVIM MMALFSIYTG
LIYNEFFSVP FELFGPSAYG CHDPSCSDAS TAGLVKVRAT YPFGVDPKWH GTRSELPFLN
SLKMKMSILI GVAQMNLGII LSYFNAKFFK NEINIWYQFV PQLIFLNSLF GYLSLLIVVK
WCTGSQADLY HVMIYMFLSP TDDLGENQLF FGQKFLQIVL LLAALVSVPW MLFPKPFLLK
KQHEERHRGQ SYALLDSSDD DPLEMELHHG SGSHEEFEFS EVFVHQLIHT IEFVLGAVSN
TASYLRLWAL SLAHSELSSV FYDKVLLLAW G
//
