ID A0A061G4W5_THECC Unreviewed; 585 AA.
AC A0A061G4W5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein isoform 3 {ECO:0000313|EMBL:EOY24611.1};
GN ORFNames=TCM_016167 {ECO:0000313|EMBL:EOY24611.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY24611.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY24611.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; CM001881; EOY24611.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061G4W5; -.
DR EnsemblPlants; EOY24611; EOY24611; TCM_016167.
DR Gramene; EOY24611; EOY24611; TCM_016167.
DR Proteomes; UP000026915; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd14479; SPX-MFS_plant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR045264; SPXM_SPX_plant.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF75; SPX DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF03105; SPX; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..145
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REGION 467..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..485
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 66272 MW; 963D674AEC4F75BF CRC64;
MVAFGKKLKE RQIQEWQGYY INYKLMKKRV KQYAHQIEVG TLDRRHVLKD FSRMLDNQIE
KIVLFLLEQQ GLLASRLTKL REQHDALEEQ PEFSQIAELR EAYRAVGQDL LKLLYFVEMN
AIGLRKILKK FDKRFGYRFT DYYVKTRANH PYSQLQQVFK HVGLGAVVGA VSRNLHELQD
RQGSYLSIYD PPALPLQDPV VDLIKAAVDR LSYSTNFLNF LAQHALIMQE ELPAPTEEHI
DEERYHFMSL LLNLANTFLY MVNTYIIVPT ADDYSMSLGA AATVCGVVIG AMAVAQVFSS
VYFSAWSNRS YFRPLVFSSI VLFVGNTMYA LAYDMNSLVV LLLGRLFCGL GSARAVNRRY
ISDCVPLKIR MQASAGFVSA SALGMACGPA LAGILQTNFK IYKLTFNQDT LPGWVMAAAW
LVYLIWLWIS FKEPSHDVEE RPSPHASNSE PAENDALEKG LKQPLLITSE DKQEDDEDQE
GDGSEEASEE SRQPATSIAS AYRLLTPSVK VQLLIYFMLK YAMEILLSES SVITTYYFSW
STGTVAIFLA CLGLTVLPVN IVVGSYISNM FEDRSSLKSP HTFNF
//
