ID A0A061GPC3_THECC Unreviewed; 367 AA.
AC A0A061GPC3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=TCM_038630 {ECO:0000313|EMBL:EOY31655.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY31655.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY31655.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
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DR EMBL; CM001887; EOY31654.1; -; Genomic_DNA.
DR EMBL; CM001887; EOY31655.1; -; Genomic_DNA.
DR EMBL; CM001887; EOY31656.1; -; Genomic_DNA.
DR EMBL; CM001887; EOY31657.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061GPC3; -.
DR EnsemblPlants; EOY31654; EOY31654; TCM_038630.
DR EnsemblPlants; EOY31655; EOY31655; TCM_038630.
DR EnsemblPlants; EOY31656; EOY31656; TCM_038630.
DR EnsemblPlants; EOY31657; EOY31657; TCM_038630.
DR Gramene; EOY31654; EOY31654; TCM_038630.
DR Gramene; EOY31655; EOY31655; TCM_038630.
DR Gramene; EOY31656; EOY31656; TCM_038630.
DR Gramene; EOY31657; EOY31657; TCM_038630.
DR eggNOG; KOG0800; Eukaryota.
DR InParanoid; A0A061GPC3; -.
DR OMA; DMDSHIQ; -.
DR Proteomes; UP000026915; Chromosome 9.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd16667; RING-H2_RNF126-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039525; RNF126-like_zinc-ribbon.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15710; E3 UBIQUITIN-PROTEIN LIGASE PRAJA; 1.
DR PANTHER; PTHR15710:SF22; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF14369; zinc_ribbon_9; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 240..281
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 133..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..322
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 40889 MW; 054052CE1B51A8CB CRC64;
MEEAMAARYW CHQCSRIVNP IMEVEIKCPV CETGFIEEMS SGTRDSEDID SDIGSDRALS
LWAPILLGMM GNPRRRRRHR RIDFEEEDDD NDDGEARHGG DTDLDRELES IIRRRRRSSA
TILQLLQGIR DGMASEAENS ENDRDRDTSR DRDRERERVI LINPFNQTII VQGSYDSNQG
GQNQNSNHIG SLGDYFVGPG LDLLLQHLAE NDPNRYGTPP AQKEAIEAMP TVKIEENLQC
SVCLDDFEAG SEAREMPCKH KFHSGCILPW LELHSSCPVC RYQMPADESK LDTERPRNNT
NQRESENNVH GSGEEGEGDG RSGSGRRFSF PWPFNGLFSS GSQAGGGNSS SASSGSQSGS
ASQADEN
//
