ID A0A061GRL5_THECC Unreviewed; 559 AA.
AC A0A061GRL5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Carotenoid cleavage dioxygenase 8 {ECO:0000313|EMBL:EOY29749.1};
GN ORFNames=TCM_037195 {ECO:0000313|EMBL:EOY29749.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY29749.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY29749.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; CM001887; EOY29749.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061GRL5; -.
DR STRING; 3641.A0A061GRL5; -.
DR EnsemblPlants; EOY29749; EOY29749; TCM_037195.
DR Gramene; EOY29749; EOY29749; TCM_037195.
DR eggNOG; KOG1285; Eukaryota.
DR HOGENOM; CLU_016472_1_2_1; -.
DR InParanoid; A0A061GRL5; -.
DR OMA; WKSVRQE; -.
DR Proteomes; UP000026915; Chromosome 9.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0010436; F:carotenoid dioxygenase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016121; P:carotene catabolic process; IBA:GO_Central.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000313|EMBL:EOY29749.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00022964,
KW ECO:0000313|EMBL:EOY29749.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915}.
FT BINDING 245
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 295
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 362
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 552
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 559 AA; 62513 MW; FC692319A8A366F7 CRC64;
MDSLSFSGIC RYRVSPSTRL EFDQSNNRKD GFSLGNKASF DRKQDRQGLA ITRVASPLKQ
AIVPSLEKET VPDQNHVAWT SVRQERWEGE LVVQGEIPLW LKGTYLRNGP GIWHIEDYNF
RHLFDGYATL VKLHFENGRL IAGHRQIESE AYKAARKNKK ICFREFSEVP KHENFMAYVG
DLAKLFSGAS LTDNANTGVV KLGDGRVVCL TETQKGSLVI DPNSLETLGR FEYSDSLGGL
IHSAHPIVTD SEFLTLLPDL LNPGYLVVRM EPATNERKVI GRVNCRGGPA PGWVHSFPVT
EHYVIVPEMP LRYSAQNLLK AEPTPMYKFK WHPESKAFLH VMCKASGKIV TSVEVPLFVT
FHFINAYEEE DEDGRVTAII ADCCEHNANT AILDQLRLQN LRSFNGQDML PDARVGRFTI
PLDGSPFGKL ESALDPDEHG RGMDMCSINP ANLGKKYRYG YACGAHRPCH FPNTLTKLDF
VKKKAKNWHD EGAVPSEPFF VARPGVTEED DGVVISIVSE KNGSGYALLL DGSTFEELAR
AKLPYGLPYG LHGCWVPKK
//
