ID A0A061H6D8_9BASI Unreviewed; 1273 AA.
AC A0A061H6D8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Aquaporin {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFL1_04693 {ECO:0000313|EMBL:EPQ27555.1};
OS Pseudozyma flocculosa PF-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Pseudozyma.
OX NCBI_TaxID=1277687 {ECO:0000313|EMBL:EPQ27555.1, ECO:0000313|Proteomes:UP000053664};
RN [1] {ECO:0000313|EMBL:EPQ27555.1, ECO:0000313|Proteomes:UP000053664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF-1 {ECO:0000313|EMBL:EPQ27555.1,
RC ECO:0000313|Proteomes:UP000053664};
RX PubMed=23800965; DOI=10.1105/tpc.113.113969;
RA Lefebvre F., Joly D.L., Labbe C., Teichmann B., Linning R., Belzile F.,
RA Bakkeren G., Belanger R.R.;
RT "The transition from a phytopathogenic smut ancestor to an anamorphic
RT biocontrol agent deciphered by comparative whole-genome analysis.";
RL Plant Cell 25:1946-1959(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O(in) = H2O(out); Xref=Rhea:RHEA:29667, ChEBI:CHEBI:15377;
CC Evidence={ECO:0000256|ARBA:ARBA00034651};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|ARBA:ARBA00006175}.
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DR EMBL; KE361638; EPQ27555.1; -; Genomic_DNA.
DR RefSeq; XP_007880413.1; XM_007882222.1.
DR AlphaFoldDB; A0A061H6D8; -.
DR GeneID; 19318794; -.
DR KEGG; pfp:PFL1_04693; -.
DR eggNOG; KOG0224; Eukaryota.
DR HOGENOM; CLU_263749_0_0_1; -.
DR OrthoDB; 5490746at2759; -.
DR Proteomes; UP000053664; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR GO; GO:0015791; P:polyol transmembrane transport; IEA:UniProt.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR43829; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR PANTHER; PTHR43829:SF9; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR PROSITE; PS00221; MIP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053664};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 856..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 937..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 989..1014
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1026..1044
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1136..1273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..766
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 780..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1189..1203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1273 AA; 135664 MW; 86D8922745BC33A4 CRC64;
MHHPAPSFDA VRPRRDDSTS GNNDDENHDG LDGHASGSRP LSASSSHPVL AFDPTDFDTR
IKLPSSSAAA PGHEAYAFSP PEPPTQRQPG PQPEQSDDEE TRSPQASRRT DEDEQLGQLI
ALDFAEQSAP QHQPPPPPSL DTEQFPTEQD SAPLQTLPEG RRVSGFEAPP DAGDSTSAPR
KQQQQQQQQP QEQPEQPEQP RYPQRATYFD TAQRSRSIAA LDQTSPRRSV QSPDEEPFGG
GPAPPPASSA RHLSTGRSPD SYQEPAPYAG PGLVGRQLSE RRAPAAYAQP EDWTYAGPSN
SASFHSSAPG TSDRHRTPQE LNAKYGSKYV PVTANEPVPE KPVWSLGSTL PRVRRAPKSV
KTIDRQSRPR VGASQSSENA KRPFSWLGRG KTLEEARSVS KRSASGNEVG CSESEEGHNR
SHDELRDSGR LPRGQALATL GSAARLTQDV RKGWHDEDRA AGSHGPLEPG KRPDDGAADL
AEIDVDRSLM ALARHSRPSV PFDENDRREG QHGPPHGDDK AGRRLREARQ RLLQEADEIQ
ARSAGDARKD ILTDEAVHQD EEGDPVPIKE GSTSRADHVQ RRQSQPGSAQ RRSGSHGQSG
LGTRGAGGGG GAGNGGDNDS KLPENSSSMD QTRHPGLSGA RPPPRGRTAG GPAVGVGTRH
ASNVSASAQH HEAPQLQRSA SSHMSARTRR SSHPTSLRRR GHPPASQAGR DLGGRADDQS
TDPAQGDDQL RKSTSSSQPT TDDGRIGHIE ARQAAGPRKS DEEGGRRSGG GGGGGGEDTR
TAWMQNSMGR QSASSDVTAT NSDSQYRLHD DDDDDDDDGA GRFQRRASET YDAVDDLQRI
AFPNLWSKWR FYSREFLAEL VASVLLLVIG TGVNCQVRLS AAMNSTGGSY TSQNTAWGLA
IMSSIYLSGG RSGAHVNPAI TLTLAVYRGF PWKQVPVYWS AQLLGAFIGA AITYSLYLPA
LNEYEGGPDV RTLTGDHGSG ELFVTVPQIV TTVASGFGTE LVATTILTVM VLAVGDETNA
PPGDGMTAVV LGLVLIMGNM ALGWSTGFAV SPSRDLGPRI LLACLGYGRE IWTHNSSWWL
YGPQAGCFAG AILGGLIYDL TIFTGGESPI NYTREAWQDA TPSRLVRPLQ EAVARSQRQK
AWRASGQGDD DGDDDGDDGS SFGRGQGNGT SDGRGRARFG GLFSKRVMGG RAAKEEADRL
ANKVRDGGGG SSRASSAASS LSSGRGGGDP APQRQLDVRP GQGGNDWPTS QHSASMLELQ
ERGGVDVGGG GRR
//
