ID   A0A061IT02_TRYRA        Unreviewed;       462 AA.
AC   A0A061IT02;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Epsin {ECO:0000313|EMBL:ESL06068.1};
GN   ORFNames=TRSC58_06263 {ECO:0000313|EMBL:ESL06068.1};
OS   Trypanosoma rangeli SC58.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX   NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL06068.1, ECO:0000313|Proteomes:UP000031737};
RN   [1] {ECO:0000313|EMBL:ESL06068.1, ECO:0000313|Proteomes:UP000031737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC58 {ECO:0000313|EMBL:ESL06068.1,
RC   ECO:0000313|Proteomes:UP000031737};
RA   Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA   Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA   Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA   de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA   Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA   Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA   Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESL06068.1}.
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DR   EMBL; AUPL01006263; ESL06068.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061IT02; -.
DR   EnsemblProtists; ESL06068; ESL06068; TRSC58_06263.
DR   VEuPathDB; TriTrypDB:TRSC58_06263; -.
DR   OrthoDB; 1532at2759; -.
DR   Proteomes; UP000031737; Unassembled WGS sequence.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   CDD; cd03571; ENTH; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   PANTHER; PTHR12276:SF45; ENTHOPROTIN-RELATED; 1.
DR   PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000031737}.
FT   DOMAIN          15..146
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   REGION          159..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..185
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..289
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   462 AA;  51173 MW;  AC0B4714995D1585 CRC64;
     MNIPTSIHAA RELIRVKASG NEFVLLVHEA TNWEPWGPTG TQMDEVCRAF SRGSVDIMEE
     IKLRLKNRDK SWRPCYKSLL LLDHLARNVP ESGLPAVCSV IPMLRTISQS FYYTGSKGTD
     HGLSVRERAK RLCDLLSDSA LLREEREKAA LTRFKLSGAS GSGGGDYSAS RYQGYSRNTL
     PSSDLPPSAY ELHTHATRTK EEQERNDMEL ATRLQREEEM RAGMSAADVE QMFHRQLPRQ
     HASVAQAARD SDHEIARRLQ EEEQKRQERH TSEALRPAQG TSTRTPAKPP SPKTAAPAPK
     PEHEPPKKDF LDDLFAPAPV MTTTTSAQQP TWTNSAPLQQ QTLASVDPFD AFLDARIQST
     TTVNSTTKQM GVMGRPFFDS KFRNSGFTPQ LNRGTYLTWD LVVGRGRGRD GPSGAVLREL
     GRRPTTYVVV GRYVSGTGVN GGYPGRGSYG LTGTEPGSLT RT
//