ID A0A061IYZ2_TRYRA Unreviewed; 662 AA.
AC A0A061IYZ2;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=Pescadillo homolog {ECO:0000256|HAMAP-Rule:MF_03028};
GN ORFNames=TRSC58_06071 {ECO:0000313|EMBL:ESL06257.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL06257.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL06257.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL06257.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000256|HAMAP-
CC Rule:MF_03028}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL06257.1}.
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DR EMBL; AUPL01006071; ESL06257.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061IYZ2; -.
DR EnsemblProtists; ESL06257; ESL06257; TRSC58_06071.
DR VEuPathDB; TriTrypDB:TRSC58_06071; -.
DR OrthoDB; 169151at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR HAMAP; MF_03028; Pescadillo; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR010613; PES.
DR PANTHER; PTHR12221; PESCADILLO - RELATED; 1.
DR PANTHER; PTHR12221:SF6; PESCADILLO HOMOLOG; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF06732; Pescadillo_N; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03028};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03028};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03028}.
FT DOMAIN 308..394
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 544..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..654
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 76702 MW; EDA86767E47FC8A7 CRC64;
MHRKQVWAKR VKKERLKKKF LTRMQATRLL QVDSIQFRRL CILKGIYPRA LARSKQKQSG
NDKQYYLARE IKWLVRDHLA ERMMAHRAWE KKVRRAEAMG LADDLKVLRS KKVKPQYSLV
ATIKERYPFF IDAVRDIDDA MSMIALYAFL SPEVMSETTI ETHHVLTSGL HEQAREISER
WNRYVTRAHV LSKGFISIKG YYFEAIVRGE RVRWLCPHEY AHKFPPGIQQ YITLSFLEFY
VELMRFVLFK LERDLERDIA EQQRTEDDGL NAHAEDFRIT DKETTQALSG VKKDVLSKVE
LMQEELRKAQ RVFEGLTFYI SREVPHKHAT LIIEACGGRV ATAYVADNIT HFVVDRPALP
SGFERVDRIE YVQPQYLFDC LNARMLLPSN GYRLGEELPP HVSPFTVAIT NSAEDVAAVE
EAKKNHPKIV SYVPKRVHDI RTLVDPQYTP IDPEGKASEL LLYDESYEEH AGVPELGADD
DVSLSGDELV EASRRPTWEE EEVTENVLRS KVSALKVAKQ RSMNLMNAPT DEVVARRRLA
QLKLRESRQQ QESSEKRLKR KLAEAKRQEA ATRKMQLQVA RKKAARYYKM VNGVVQGSQR
REKMLEAKAK QLADGRVAMK KDGRELVNTR MEAKRAKAEA AGKPLREKKV ASPYKKLPKW
VR
//
