ID A0A061J2F3_TRYRA Unreviewed; 739 AA.
AC A0A061J2F3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Long-chain-fatty-acid-CoA ligase protein {ECO:0000313|EMBL:ESL08326.1};
GN ORFNames=TRSC58_03973 {ECO:0000313|EMBL:ESL08326.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL08326.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL08326.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL08326.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL08326.1}.
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DR EMBL; AUPL01003973; ESL08326.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J2F3; -.
DR EnsemblProtists; ESL08326; ESL08326; TRSC58_03973.
DR VEuPathDB; TriTrypDB:TRSC58_03973; -.
DR OrthoDB; 5473537at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ESL08326.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737}.
FT DOMAIN 115..573
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 635..726
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 199..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 739 AA; 81780 MW; 159D272C1F06D53B CRC64;
MFCVVRRRLD KVPFATLFGY NSILQSVFSA PVKEEAIVVE LPGGRTERYT YGQLQKDVLS
MSNVITERRE AVTVARGKPS LSWLQQPRPS NVRSIFADGD GGVLSCDFMK DDGQHNVAII
GTTGYTFVVS LLAAWSLNQM AVPIPASQNC TAELSYILEH SRSRAVMGDT VPLKANLPRQ
YDALLVRSFS SLHNPMAAAT TTTTTTTTTT SSSSSSTPST YDVETLFDVQ KLLEKIKEKC
EISEAATTVI LPDHLLSEEE RHQLKDAHDI MNRISDEKAV SEERREALRQ YMIREHFKAH
CAVTDAEDGT GLFYDTDHLD SLNVVHRLWA EECAARPSKH DDCVMIYTSG TTAKPKGAVH
THASLQNMVR VLRKAWEWSS KDTILHTLPV YHIHGLVNIL LCCLASNARC ILTKFDDPLR
IARRLERGDI TLMMGVPTMY TKLIAAVNQK MSPIEQAGFK NAVSQNVRLM VCGSAPLPVP
IIQAFREISG HTLLERYGMT EIGMALSQSL RPVEKRIPGT VGSPLPTVRA FVHGASAATG
EESGSAGGEG GQGHYDEVGQ LAIASKSLFD RYWRNPEETK KVLVVSQEGR RYFDTGDTVG
VSTPRNKNED AIFTILGRAS MDILKCRGFK LSALEIEAAL ISRQDLFFEI VVVGCKDDML
GEEVVAIIAP QPAALQKWSI PPDFDRFESP ELNAELKAVA RSFLSYYKCP SRFILLPEIP
RNPTGKVNKK NLKEKLSLA
//
