ID A0A061J2S1_TRYRA Unreviewed; 756 AA.
AC A0A061J2S1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Ribosome biogenesis protein ERB1 {ECO:0000313|EMBL:ESL08595.1};
GN ORFNames=TRSC58_03699 {ECO:0000313|EMBL:ESL08595.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL08595.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL08595.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL08595.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL08595.1}.
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DR EMBL; AUPL01003699; ESL08595.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J2S1; -.
DR EnsemblProtists; ESL08595; ESL08595; TRSC58_03699.
DR VEuPathDB; TriTrypDB:TRSC58_03699; -.
DR OrthoDB; 5472008at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR17605:SF0; RIBOSOME BIOGENESIS PROTEIN BOP1; 1.
DR PANTHER; PTHR17605; RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW Signal {ECO:0000256|SAM:SignalP};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..756
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001601530"
FT DOMAIN 183..446
FT /note="BOP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01035"
FT REPEAT 453..494
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 86..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..359
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 85785 MW; B079D23E3B0057BB CRC64;
MFFLYTFIIL FFIFFVTVCT DERCLVRYQG MPLRRGSASR GVQRVETPRM AREMPAAKAR
KMSSCAGTAT PPLDAAATAA APAEDLPLTP HSKQPVAEEA PSNEDLPPTT ALALRDEVIW
SDSDDDNGDG SVLLFPDAQD LVEKPGSTLN LIRVGTTQKL DESDSSEDEA TLNRVGDIPP
EWYKDEAHFG YDVEGRKLMK SERSALERLL EATDDPNALR TIYDALHDEN KKLSNADLQM
IFNLQRNRTP NANYNMYADV VTDSVEFDPL NHPLARAGGP SKKKFVPAQH DMKVIEKMVR
RLMKAEGNKT DEKEETLPDE PLVIWDDSKV EMEAHAKFKY QNRVPKPKVP PPGTYESYRP
PPEYLPSDKA RQRFARLRQI DRKEHFLPQA FEALRHVPFY HHTIQDRYQR CLDLALFPRA
QRTRLVVDPS KLLPDLPDPK DLRPYPERLS FQYKGHTATV RSVSVSPNGQ FLATGCDDHL
VRVYEVMTGR LMKRYDMGGP VQQVEFCPVK ALNILAVAVE YSLVFIVPTF AAHQVVNEHT
IRYLRAPGSA LAQSTENHIV GGEASLRGGG ITQTTLDKDE SAHRLLHDLH DTEEREKRAE
FVDASAQERS AGIVVKIALH GKVKRFTFHA RGDYLCALCP KDHVKYRQTV MLQLSKRKVF
CPFRKFSEIV TDCKFHPREP LFFLATTNSV RVYNLMAHRL QRRYKAPGGI TTCLSVHTEG
DNFLVGDTTS HTQWYDCDFS DKPYKRMRSH KGVSTP
//
