ID A0A061J4Y2_TRYRA Unreviewed; 746 AA.
AC A0A061J4Y2;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=TRSC58_03930 {ECO:0000313|EMBL:ESL08367.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL08367.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL08367.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL08367.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL08367.1}.
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DR EMBL; AUPL01003930; ESL08367.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J4Y2; -.
DR EnsemblProtists; ESL08367; ESL08367; TRSC58_03930.
DR VEuPathDB; TriTrypDB:TRSC58_03930; -.
DR OrthoDB; 123594at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000031737}.
FT DOMAIN 366..558
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 746 AA; 83729 MW; 7C1D5429230966E2 CRC64;
MRGGGDVMNE EVRRILNEPT RQQVLRRLLM EVLRRRREWK SGVPSCEAVG AVRPGCPDTN
AQLHELQESK KRLRQMPTNC AVAIAELLQL QPQSARGGER LLVTTVLQSV VQGCQSFFPR
EALLSLLHSD TSEEARRVFL VKTWPQYWDS ELAMTRELLG VVEESVKGLL TKLVFLWEAG
SDAPVHGPLN TASGLQHCYV SHLLQVTLRP LLEELFALDA TSKESATRGP LMVLLDIAQG
MACVEAPPQG APQLWEQVGA GTVLLGDFPR EVGYVAMAEV CRGLLEARLT AAVEHFLGSG
DLTEEQRGLR LLAYLLRTER VFCLLCEVQP LGARLRDSGG AVGCFYGIVK HAVANHLHRS
RGADVFADTL LESMQAYILQ RNRERAAVAA LLLRNEDEFL SAVRLTQSVV STDRYLRVYK
ELLAYRLLYY MVGRARDGGL DAAEARREKV QAEKAACEHL QKLFPLECDT VRQMVQMCLD
MEAGEEAQVG HDPLVPQEEQ GGATEEAAVR PVLWLLSRRA WPSYPVLEDA PRPLLQAMRQ
FARVYHAQHR DRRIVWLRTS METITFTVGY PKATKVIVGS LELFNIFHCL SEAGAAGAPW
TLLAQRIGKG KTMLQRGLKK LLNDGFFTVH AGAEEECVAL NAIFTSHRSR YHFLQQPPRV
GALAEAPRTI TEEAHLSHAG AIMAAVIKHM KRVRTCMYDE LFRAAQQQNP QFQLQNSDFK
MALETLIEKE FVVRDPVRKQ WFVYEA
//
