ID A0A061J672_TRYRA Unreviewed; 556 AA.
AC A0A061J672;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=FYVE, RhoGEF and PH domain-containing protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRSC58_01331 {ECO:0000313|EMBL:ESL10928.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL10928.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL10928.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL10928.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL10928.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AUPL01001331; ESL10928.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J672; -.
DR EnsemblProtists; ESL10928; ESL10928; TRSC58_01331.
DR VEuPathDB; TriTrypDB:TRSC58_01331; -.
DR OrthoDB; 169617at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46622; DNA-DEPENDENT METALLOPROTEASE WSS1; 1.
DR PANTHER; PTHR46622:SF1; DNA-DEPENDENT METALLOPROTEASE WSS1; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00641; zf-RanBP; 3.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00547; ZnF_RBZ; 5.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR PROSITE; PS50178; ZF_FYVE; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 5.
DR PROSITE; PS50199; ZF_RANBP2_2; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00322}.
FT DOMAIN 224..255
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 289..320
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 341..370
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 387..417
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 442..471
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 496..554
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 193..230
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 23..42
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..80
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 60546 MW; B3C062A85B59E71F CRC64;
MNFDLDELFD TRPRQQQQQH GGPTYVPPPP PSDPPPPPVW MQQDPFGMNA TAAQQQQQQP
PPPPPPPPPP LPPPPMQPFE VATYAPATAV PYQTHYLPSH APQSYGENGY KLPSSSLPSG
GLSAALPAQT AYYAEPTSTP VHHGPSYQAS LGVPDAPSIP QTVRSSAVPS VPPPSQSEPA
VMTPIAVKES SVLAQEEEDR KQLEKIIQLR KELEKERERE RKKQEELETW GCSSCTYRNA
LDVNRCEMCD SNRPGYLPPP NVAPPSTAHS DARSSFPSSS KTTGVQSGVA GPTAWVCGIC
LAPNEAHHFR CKVCGSYQKN GTPITGVDAK ATGTTPGVYM PPSAWLCGIC GKKNAANAAR
CVGCSSYQSN GTPLMDPGLT PQTVTETAST TWKCSVCTLE NPVSSVVCDA CQSGQRPRHL
APPRTNDRTK NKSGAESRDA NVARTWPCPT CTYQNAIVRE KCDMCTTERP SQYKPPPPPN
TKEAEDSDDD IQWQDDEAAK ECNRCHLPFN LTRRRHHCRA CGFVFCGVCS SYQRALKRNG
SLERVCVSCY EAQKRE
//
