ID   A0A061JDX6_TRYRA        Unreviewed;       876 AA.
AC   A0A061JDX6;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Heat shock 70 kDa protein {ECO:0000313|EMBL:ESL11587.1};
GN   ORFNames=TRSC58_00658 {ECO:0000313|EMBL:ESL11587.1};
OS   Trypanosoma rangeli SC58.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX   NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL11587.1, ECO:0000313|Proteomes:UP000031737};
RN   [1] {ECO:0000313|EMBL:ESL11587.1, ECO:0000313|Proteomes:UP000031737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC58 {ECO:0000313|EMBL:ESL11587.1,
RC   ECO:0000313|Proteomes:UP000031737};
RA   Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA   Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA   Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA   de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA   Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA   Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA   Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESL11587.1}.
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DR   EMBL; AUPL01000658; ESL11587.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061JDX6; -.
DR   EnsemblProtists; ESL11587; ESL11587; TRSC58_00658.
DR   VEuPathDB; TriTrypDB:TRSC58_00658; -.
DR   OrthoDB; 148304at2759; -.
DR   Proteomes; UP000031737; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10170; HSP70_NBD; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   PANTHER; PTHR19375:SF562; SHOCK 70 KDA PROTEIN, PUTATIVE-RELATED; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031737};
KW   Stress response {ECO:0000313|EMBL:ESL11587.1}.
FT   REGION          657..702
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          845..876
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          601..635
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        657..686
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        688..702
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   876 AA;  97906 MW;  782C10D041AC58CB CRC64;
     MRCSSVFLLR RTRMGLQQLP MPMPPRRPGS SVNMQHSMEL EAKRRMELDE ATRHRFVVVK
     EATTARNGRV IGIDLGTTNS CISYVDDATS RPKIIPSPTG SWVFPTAITF DKNHKVRLYG
     EEARACVRTS ASATLCNGKR LIGRGVGELG RVQSQLHKTN MLTLNEKGEV AVEIMGRTYT
     VVHIIAMFLR YLKHEAEKYL KEPVDAVVVS VPAFFTPQQK VATEDAALAA GFDVLEVIDE
     PSAACLTHTA LRRDEEEGAA KQKPHSRQRV VRSLVFDLGG GTLDCAIMEH NQRSGVFTLV
     ATHGDPLLGG NDWDAVLSQH FLEQFERKWR VPLEDAEGNV GQGVATYRQL LLEAEKAKVH
     FTHSTEPYYG YNRAFHFSER LRDIVPLEAT LTHEEYVALT RPLRVRCIEC LNKLFDHTGI
     QVRDIDNVLL VGAMTRDPPI RHMLSEYFGR PVAPENTCPA DYAVAIGAAI RGAMLQGKFN
     DLSANTRFVS GTAQAMRHGG PIRRLWNRMN TWITRSVNPN AIGQRWRGRA KGLSDNEIAN
     YAKELVEFEA ACQRRLLLER AENDANFVMR RVTADSNKRQ GMQEKRVRQL GEQLKFWQYM
     VHNFHDHEEE LQRTVKELEQ ALDELEGYAE DNTAALTSEG TVNFAKATPV NNCSEGDIAN
     NASKSPSSPA RAATISATSS LGSEMAHNRP EGQKERQRSP KIIRRPVPLP KASAEAQELV
     EAGHPALRGA DVTMTESTRS SFFEAQVEER AWREPPTPPG EEGSWQEVKR AVEAGEEVGS
     PISPQELQRP MTHEEMLQVL LTMAPIDDPI SEEHAKRRDL ALDLQTMTVV EGMVDMAALE
     SRLEAAARAK EESQQAQKRA EMNAPADTSA SLFRRD
//