ID   A0A061PAQ8_9BACL        Unreviewed;       435 AA.
AC   A0A061PAQ8;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Xanthine/uracil/thiamine/ascorbate permease family protein {ECO:0000313|EMBL:GAK13329.1};
GN   ORFNames=JCM19039_3169 {ECO:0000313|EMBL:GAK13329.1};
OS   Geomicrobium sp. JCM 19039.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Geomicrobium.
OX   NCBI_TaxID=1460636 {ECO:0000313|EMBL:GAK13329.1, ECO:0000313|Proteomes:UP000027177};
RN   [1] {ECO:0000313|EMBL:GAK13329.1, ECO:0000313|Proteomes:UP000027177}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 19039 {ECO:0000313|EMBL:GAK13329.1,
RC   ECO:0000313|Proteomes:UP000027177};
RA   Kudo T., Nakahara T., Zhang X., Taniyama S., Arakawa O., Murase S.,
RA   Nakata H., Oshima K., Suda W., Kitamura K., Iida T., Oshida Y., Inoue T.,
RA   Hongoh Y., Hattori M., Ohkuma M.;
RT   "Draft Genome Sequences of Geomicrobium sp. Strains JCM 19037, JCM 19038,
RT   JCM 19039, and JCM 19055, Isolated from Aquatic Samples.";
RL   Genome Announc. 2:e00622-14(2014).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAK13329.1}.
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DR   EMBL; BAXB01000015; GAK13329.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061PAQ8; -.
DR   Proteomes; UP000027177; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337:SF11; GUANINE_HYPOXANTHINE PERMEASE PBUG; 1.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027177};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        46..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        247..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        381..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   435 AA;  45980 MW;  4FA405162D44FD13 CRC64;
     MKNYFNFAEH GTSYKRETLA GFTTFLAMAY ILAVNPLILG DAGMDANAVF VATAIAAAIG
     SFIMGLWASY PIALAPGMGL NAFFAYTVVL GMGIDWQIAL FGVFLSGIIF LIITLFKIRE
     VIINAIPSEM KYAAGAGIGL FIAFIGLQNA DIIVLDEATL VSLGDLSNPY TLLAMFGVVI
     TACFMVLKLR GGVFYGMVAT AIAGILFGLI QPPSGIISSI PSLAPTFGAA FTHLGEVQWT
     TEMILQLSIV VITFLFVDFF DTAGTLYAVA QQAGFVKDNK LPNAGRALLS DASATSIGAI
     LGTSTTTAYV ESSAGVAAGG RTGFTAIVTA GFFLVALFFS PLLEVVTSHV TAAALIIVGV
     LMASSLRLIE WDRIEVAIPA FLVVVGMPLT YSIASGIALG FMFYPITMVL AGKGKNVHPI
     MYALFFIFVG YLFFL
//