ID A0A061PIH4_9BACL Unreviewed; 735 AA.
AC A0A061PIH4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:GAK14510.1};
GN ORFNames=JCM19039_4436 {ECO:0000313|EMBL:GAK14510.1};
OS Geomicrobium sp. JCM 19039.
OC Bacteria; Bacillota; Bacilli; Bacillales; Geomicrobium.
OX NCBI_TaxID=1460636 {ECO:0000313|EMBL:GAK14510.1, ECO:0000313|Proteomes:UP000027177};
RN [1] {ECO:0000313|EMBL:GAK14510.1, ECO:0000313|Proteomes:UP000027177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 19039 {ECO:0000313|EMBL:GAK14510.1,
RC ECO:0000313|Proteomes:UP000027177};
RA Kudo T., Nakahara T., Zhang X., Taniyama S., Arakawa O., Murase S.,
RA Nakata H., Oshima K., Suda W., Kitamura K., Iida T., Oshida Y., Inoue T.,
RA Hongoh Y., Hattori M., Ohkuma M.;
RT "Draft Genome Sequences of Geomicrobium sp. Strains JCM 19037, JCM 19038,
RT JCM 19039, and JCM 19055, Isolated from Aquatic Samples.";
RL Genome Announc. 2:e00622-14(2014).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAK14510.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAXB01000035; GAK14510.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061PIH4; -.
DR Proteomes; UP000027177; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 2.20.70.70; -; 1.
DR Gene3D; 3.30.70.2110; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 2.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000027177};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 646..703
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 683..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..735
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 82141 MW; F7A436D94179A9A2 CRC64;
MKRTTIVYRA LIVFAFAAFL LAVIGGRFLY VQIAQGTEEH DYLQYAERQW TSEQPLHGER
GTFTPVTKVL LQKRCLRIQS NSFCEMTLGM PGLKTLLKPH GSRLTLIWRK ASCYQRIENG
MEEDQFQIEL GPGASYLTFE QRQAIDDLEL SGIEFRTEPR RYYPKQDFAS HVVGYFNRNE
NSPAMGLESY LNDHLEGTGG SYSYMRARNG VPLPGEIRDI EEAYNGDDIH LTLHSNIQLA
VEQALTNADE QYSPERMIAV VANPKSGEIL AMSNRPSFNP NHYESISNHM NFAVSDHFEP
GSTMKIFTMA AAIEEGVYEP DNYFESGTYN TGYADTPLIR DHNQGRGWGS IPYREAMPRS
ANTAFASIVN DQLGAERFYE YMNAFGFGSP TGIELPMEAP GSCQKMIWVP SILGLDKLLL
RQFNKSKQRP PLPTMQMVKP YLIDSIVNPN TGDVTYEHER EVIGEPISKE TANEVMEQLR
DVVYSDVGTG KPFQVDGIEV AGKTGTAQIP SEGGYLQGRN QNVFSFLGMA PFDDPEVIVY
VAVDRPDMPN DQSGNQAVAE IFNSVLKQSI QYLNVTPEEF DNQAYQPEGA ELMNVSGERR
SDAVDVLQQE NFEPVILGQG NRVEAQLPAP HAKVLAGEKV FLYLGGEMAM PDLSGWSVRD
VMKFSQASGV TVEQSGNGYV TNQEIAPGEP ISGNETIEVN FDSERISDEV DEDSEEGTEE
ENPETNDEEV ENEDE
//
