ID A0A062VUZ6_9MICO Unreviewed; 547 AA.
AC A0A062VUZ6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=DC31_11770 {ECO:0000313|EMBL:KDA05946.1};
OS Microbacterium sp. CH12i.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1479651 {ECO:0000313|EMBL:KDA05946.1, ECO:0000313|Proteomes:UP000027096};
RN [1] {ECO:0000313|EMBL:KDA05946.1, ECO:0000313|Proteomes:UP000027096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH12i {ECO:0000313|EMBL:KDA05946.1,
RC ECO:0000313|Proteomes:UP000027096};
RA Ferreras E.R., DeMaayer P., Guerrero L.D., Aislabie J.M., Cowan D.A.;
RT "Draft genome sequence of Microbacterium sp. strain CH12i, isolated from
RT shallow groundwater in Cape Hallet, Antarctica.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDA05946.1}.
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DR EMBL; JHET01000006; KDA05946.1; -; Genomic_DNA.
DR RefSeq; WP_036278486.1; NZ_JHET01000006.1.
DR AlphaFoldDB; A0A062VUZ6; -.
DR STRING; 1479651.DC31_11770; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000027096; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:KDA05946.1};
KW Helicase {ECO:0000313|EMBL:KDA05946.1};
KW Hydrolase {ECO:0000313|EMBL:KDA05946.1};
KW Nucleotide-binding {ECO:0000313|EMBL:KDA05946.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027096}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 399..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 547 AA; 60446 MW; 136DBF5484A30DE3 CRC64;
MSDGPLIVQS DRTVLLEVAH ADAESARHEL AIFAELERAP EHIHTYRITR LGLWNARAAG
HTADDMLATL DRWSRFPVPP SVSVDLRETV NRYGRLVIER DDKGTLLLRS IDPAVLTQVA
NNKRIQPLLV GHPSPDSYAV DAWARGQIKQ ELLKIGWPAE DLAGYTPGTP HEIDLAEDGW
HIRPYQQDAV DAFAKDGSGV VVLPCGAGKT IVGAGAMATT KTTTLILVTN TVSARQWRDE
LLKRTSLTAE EIGEYSGQVK EVKPVTIATY QILTAKRKGE YAHLALLDAL DWGLIIYDEV
HLLPAPVFKL TADLQARRRI GLTATLVRED GREGDVFSLI GPKRFDAPWK QIEAQGFISP
AACYEVRVDL PADDRLEYAA ATDDERYRLA ASAPAKISAV RELIAKHPGE RILVIGQYLD
QLDTLSDALN APQITGATPI DERERLYQQF REGEIELLVV SKVANFSIDL PEASVAIQVS
GSFGSRQEEA QRLGRLLRPK ESGRTASFYT LIARDTVDQD YAQNRQRFLA EQGYSYTILD
ADALTAA
//
