ID A0A062X6S3_9LACO Unreviewed; 418 AA.
AC A0A062X6S3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=DEXH box helicase, DNA ligase-associated {ECO:0000313|EMBL:KDA46458.1};
GN ORFNames=Lani381_0478 {ECO:0000313|EMBL:KDA46458.1};
OS Ligilactobacillus animalis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1605 {ECO:0000313|EMBL:KDA46458.1, ECO:0000313|Proteomes:UP000027129};
RN [1] {ECO:0000313|EMBL:KDA46458.1, ECO:0000313|Proteomes:UP000027129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=381-IL-28 {ECO:0000313|EMBL:KDA46458.1,
RC ECO:0000313|Proteomes:UP000027129};
RA Sturino J.M., Rajendran M., Altermann E.;
RT "Draft Genome Sequence of Lactobacillus animalis 381-IL-28.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDA46458.1}.
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DR EMBL; JMHU01000004; KDA46458.1; -; Genomic_DNA.
DR RefSeq; WP_035447412.1; NZ_POVP01000003.1.
DR AlphaFoldDB; A0A062X6S3; -.
DR PATRIC; fig|1605.9.peg.478; -.
DR eggNOG; COG0513; Bacteria.
DR OrthoDB; 9805696at2; -.
DR Proteomes; UP000027129; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProt.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Ligase {ECO:0000313|EMBL:KDA46458.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492}.
FT DOMAIN 3..281
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT DOMAIN 25..195
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 225..365
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 373..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..418
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 46955 MW; F55B67A8D654526E CRC64;
MNPKFENYFK EQGFKDLTPI QAGVAPLLAR GESVLGLAPT GSGKTLAYAL PLLEQLLPKD
GTQLLILAPS QELAAQLTNV IRPWAKLLEL NVLSLIGGAN VKRQIEKLKK RPEVVIGTPG
RLLNLINDKK LKLHKLEAIV IDEADELLGE AETLADCREI IAHAPGEVAV SFFSATKAPI
LAELHRWFGI EPTVIDVCQV DHTQGQVDHY VLEVPQRKRV DALRRLAQLD EFCALVFFKQ
TAELNYAYEK LKHAHVNVAR LNSEQRQVER EQALRQLRKR EVALLLTTDV AARGLDIPGL
PAVVNYDLPK NVNTYIHRVG RTGRMGADGT VINIGNERDL RMFKQLVKEK GYELAPVYLY
QRQLVTDQTE LAELKKQAPS RPVRKKANKP VAQADSAKKK RKKNRKRDQK NKGKRKKS
//
